| 刘芳欣,任永凤,李健,王珊珊,曹利芳,陈昭杰.超声测量膈肌运动参数联合BODE指数预测慢性阻塞性肺疾病急性加重[J].中国医学影像技术,2025,41(1):90~93 |
| 超声测量膈肌运动参数联合BODE指数预测慢性阻塞性肺疾病急性加重 |
| Ultrasonic parameters of diaphragm motion combined with BODE index for predicting acute exacerbation of chronic obstructive pulmonary disease |
| 投稿时间：2024-07-06 修订日期：2024-09-26 |
| DOI：10.13929/j.issn.1003-3289.2025.01.019 |
| 中文关键词: 肺疾病,慢性阻塞性 膈肌 超声检查 呼吸功能试验 |
| 英文关键词:pulmonary disease, chronic obstructive diaphragm ultrasonography respiratory function tests |
| 基金项目:亳州市人民医院院级科研项目(by2023034)。 |
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| 中文摘要: |
| 目的 观察超声测量膈肌运动参数联合BODE指数预测慢性阻塞性肺疾病(COPD)急性加重的价值。方法 回顾性纳入80例COPD患者并分为稳定组(n=45)与急性加重组(n=35),以超声测量平静呼吸(QB)下膈肌移动度(DEQB)及用力呼吸(DB)下DEDB。比较组间一般资料、超声所测膈肌运动参数及BODE指数等;采用logistic回归分析筛选可用于预测COPD病情急性加重的独立因素,以受试者工作特征(ROC)曲线及其曲线下面积(AUC)评价单一膈肌运动超声参数、BODE指数及其联合预测COPD急性加重的效能。结果 相比稳定组,急性加重组BMI及BODE指数评分均较高(P均＜0.05),DEQB较大而DEDB较小(P均＜0.05)。DEDB及BODE指数为COPD急性加重的独立预测因素;DEDB增大提示COPD急性加重风险降低[OR(95%CI)=0.673(0.493,0.918),P＜0.05],而BODE指数增大提示风险增加[OR(95%CI)=3.678(1.061,12.746),P＜0.05];二者单一预测的AUC分别为0.788、0.799,其联合预测的AUC为0.979,显著高于单一预测(P均＜0.05)。结论 超声测量膈肌运动参数可用于评估COPD患者膈肌功能;DEDB联合BODE指数预测COPD急性加重的效能较好。 |
| 英文摘要: |
| Objective To observe the value of ultrasonic parameters of diaphragm motion combined with BODE index for predicting acute exacerbation of chronic obstructive pulmonary disease (COPD). Methods Eighty COPD patients were retrospectively collected and divided into stable group (n=45) and acute exacerbation group (n=35). Ultrasonic parameters of diaphragm motion, including diaphragm excursion (DE) under quiet breathing (QB) and deep breathing (DB), i.e. DEQB and DEDB were measured. The general data, ultrasound parameters of diaphragm motion, and BODE index scores were compared between groups. Then logistic regression analysis was used to identify factors which could be used to independently predict acute exacerbations of COPD. The predicting performance of ultrasound parameters of diaphragm motion, BODE index and their combination were evaluated with receiver operating characteristic (ROC) curve and the area under the curve (AUC). Results Compared with stable COPD group, acute exacerbation group had higher BMI and BODE index scores (both P＜0.05), as well as larger DEQB but smaller DEDB (both P＜0.05). DEDB and BODE index were both independent predicting factors of acute exacerbation of COPD, while increased DEDB indicated decreased risk of acute exacerbation (OR[95%CI]=0.673[0.493, 0.918], P＜0.05), whereas increased BODE index suggested higher risk (OR[95%CI]=3.678[1.061, 12.746], P＜0.05). AUC for DEDB and BODE index alone for predicting acute exacerbation of COPD was 0.788 and 0.799, respectively, and of their combination was 0.979, significant higher than that of each alone (both P＜0.05). Conclusion Ultrasonic parameters of diaphragm motion could be used to evaluate diaphragm function in COPD patients. Combination of DEDB and BODE index had better performances in predicting acute exacerbation of COPD. |
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