| 丁金,丁焕芝.优化MR子宫输卵管造影钆碘对比剂混合比例[J].中国医学影像技术,2024,40(11):1779~1784 |
| 优化MR子宫输卵管造影钆碘对比剂混合比例 |
| Optimizing mix ratio of gadolinium and iopromide contrastagents for MR hysterosalpingography |
| 投稿时间：2024-04-10 修订日期：2024-08-26 |
| DOI：10.13929/j.issn.1003-3289.2024.11.030 |
| 中文关键词: 磁共振成像 子宫输卵管造影术 对比剂 信号强度 |
| 英文关键词:magnetic resonance imaging hysterosalpingography contrast media signal intensity |
| 基金项目: |
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| 中文摘要: |
| 目的 筛选适用于MR子宫输卵管造影(MR-HSG)的对比剂混合比例。方法 配制16种不同混合比例钆碘对比剂,包括钆剂与生理盐水(GD-NS)、钆剂与碘普罗胺(GD-I370)及钆剂与碘克沙醇(GD-I320),分别以1.5T及3.0T MR仪进行扫描。对图像质量进行主观评价,比较不同对比剂图像信号强度(SI)及以不同场强MR仪所获图像SI,以SI最高图像的混合比例为最佳,并对2例患者行MR-HSG。结果 1.5T下,1:80为GD-NS最佳混合比例,GD-I370及GD-I320均以1:300为最佳混合比例;GD-NS、GD-I370、GD-I320图像SI差异均无统计学意义(P均＞0.05)。3.0T下,1:50为GD-NS、1:200为GD-I370及GD-I320最佳混合比例;3种对比剂图像SI差异有统计学意义(P＜0.05),GD-NS的SI高于GD-I370、GD-I320(P均＜0.05),而GD-I370与GD-I320 SI差异无统计学意义(P＜0.05)。1.5T下GD-NS、GD-I370、GD-I320图像的SI均低于3.0T (P均＜0.05)。以1:200 GD-I370行体内MR-HSG可清晰显示输卵管。结论 1.5T MR-HSG以1:300、3.0T MR-HSG则以1:200钆碘混合对比剂为佳。 |
| 英文摘要: |
| Objective To optimize mixing ratio of gadolinium and iopromide contrast agents for MR hysterosalpingography (MR-HSG). Methods Sixteen kinds of mixed contrast agents including gadolinium and iopromide, i.e. saline contrast agent (GD-NS), gadolinium and iopromide contrast agent (GD-I370) and gadolinium and iodixanol contrast agent (GD-I320) were prepared and scanned using 1.5T and 3.0T MR scanners, respectively. Imaging quality was subjectively assessed, and the signal intensities (SI) were compared among different contrast agents and between 1.5T and 3.0T. Taken the mixing ratio resulted the highest SI as the optimal mix ratio, MR-HSG was performed in 2 cases. Results For 1.5T scanning, 1 : 80 was the best ratio of GD-NS, 1 : 300 was the best for both GD-I370 and GD-I320, while no significant difference of SI was found among GD-NS, GD-I370 and GD-I320 (P＞0.05). For 3.0T scanning, 1 : 50 was the best ratio of GD-NS, while 1 : 200 was the best for both GD-I370 and GD-I320. Significant differences of SI were found among different contrast agents (P＜0.05), SI of GD-NS was higher than that of GD-I370 and GD-I320 (both P＜0.05), while of the latter two were no significant different (P＞0.05). SI of GD-NS, GD-I370 and GD-I320 under 1.5T were all lower than that under 3.0T (all P＜0.05). MR-HSG clearly showed fallopian tubes using 1 : 200 GD-I370 in 2 cases. Conclusion 1 : 300 gadolinium-iodine mixed contrast agents were suitable for 1.5T MR-HSG, while 1 : 200 gadolinium-iodine mixed contrast agent were suitable for 3.0T MR-HSG. |
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