黄志芳,吕仁华,丁红,薛立云,李雪齐.以剪切波速度评估慢性肾病分期的最佳肾脏靶区[J].中国医学影像技术,2024,40(11):1745~1748
以剪切波速度评估慢性肾病分期的最佳肾脏靶区
Optimal target areas for shear wave velocity evaluation on stages of chronic kidney disease
投稿时间:2024-07-26  修订日期:2024-10-14
DOI:10.13929/j.issn.1003-3289.2024.11.023
中文关键词:  肾疾病  超声检查  弹性成像技术
英文关键词:kidney diseases  ultrasonography  elasticity imaging techniques
基金项目:
作者单位E-mail
黄志芳 复旦大学附属华山医院超声医学科, 上海 200040  
吕仁华 复旦大学附属华山医院超声医学科, 上海 200040 lrhmail@126.com 
丁红 复旦大学附属华山医院超声医学科, 上海 200040  
薛立云 复旦大学附属华山医院超声医学科, 上海 200040  
李雪齐 复旦大学附属华山医院超声医学科, 上海 200040  
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中文摘要:
      目的 观察以剪切波速度(SWV)评估慢性肾病(CKD)分期时,在肾脏不同侧别(左、右)、不同部位(上极、中部、下极)及不同组织(肾皮质、肾髓质、肾窦部)中的最佳靶区。方法 回顾性收集65例CKD患者共130侧肾脏,比较肾脏不同侧别、不同部位、不同组织SWV,分析用于评估CKD分期的最佳区域。结果 左、右肾之间,相同部位、相同组织SWV差异均无统计学意义(P均>0.05);而同侧肾上极、中部及下极之间相同组织SWV差异均有统计学意义(P均<0.05),均为上极>中部>下极;同侧肾相同部位肾皮质、肾髓质及肾窦部之间SWV差异均有统计学意义(P均<0.05),均以肾窦部SWV最大。组内相关系数分析显示,肾中部SWV测值的可重复性最佳。1期、2期、3期及4~5期CKD肾中部肾皮质与肾髓质SWV差异均有统计学意义(P均<0.05),以4~5期SWV最高(P均<0.05);且肾中部肾皮质、肾髓质SWV均与CKD分期呈正相关(P均<0.01),其评估CKD分期的曲线下面积分别为0.802及0.774。结论 肾中部肾皮质、肾髓质为利用SWV评估CKD分期的最佳靶区。
英文摘要:
      Objective To observe the optimal target areas for shear wave velocity (SWV) evaluation on stages of chronic kidney disease (CKD) in different sides (left, right), different parts (upper pole, middle part and lower pole) and different tissue (renal cortex, renal medulla, renal sinus) of kidney. Methods Sixty-five CKD patients (130 kidneys) were retrospectively collected. SWV were compared between different sides, among different parts and tissue of kidney. The optimal regions for evaluating CKD stages were screened. Results No significant difference of SWV was found between left and right kidneys in same parts for same tissue (all P>0.05), while significant differences of SWV of the same tissue were noticed among upper pole, middle part and lower part of kidney on the same side (all P<0.05), i.e at upper pole> at middle part> at lower pole. Significant differences of SWV were also observed among renal cortex, medulla and sinus of kidney in the same side and parts (all P<0.05), and the sinus had the highest SWV. Intraclass correlation coefficient analysis showed that the repeatability of the measurements of SWV was the best at the middle part of kidney. Besides, significant differences of SWV were found between renal cortex and medulla at the middle part of kidney among patients with stages 1, 2, 3 and 4—5 CKD (all P<0.05), while the highest SWV were observed in patients with 4—5 stage CKD (all P<0.05). SWV of renal cortex and medulla at middle part were positively correlated with CKD stages (both P<0.01), the area under the curve of them for evaluating stage of CKD was 0.802 and 0.774, respectively. Conclusion The optimal target areas for SWV evaluation on stages of CKD were renal cortex and medulla at middle part of kidney.
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