| 钱佳佳,翟建,王钰璇,武彤,王志强,邱凯迪,罗慧.腹背部脂肪含量相关定量CT参数预测食管癌术后早期并发症[J].中国医学影像技术,2024,40(11):1725~1729 |
| 腹背部脂肪含量相关定量CT参数预测食管癌术后早期并发症 |
| Quantitative CT parameters related to abdominal and dorsal fat content for predicting early postoperative complications of esophageal cancer |
| 投稿时间：2024-06-05 修订日期：2024-08-06 |
| DOI：10.13929/j.issn.1003-3289.2024.11.019 |
| 中文关键词: 食管肿瘤 腹部脂肪 手术后并发症 体层摄影术,X线计算机 |
| 英文关键词:esophageal neoplasms abdominal fat postoperative complications tomography, X-ray computed |
| 基金项目: |
|
| 摘要点击次数: 408 |
| 全文下载次数: 112 |
| 中文摘要: |
| 目的 观察腹背部脂肪含量相关定量CT (QCT)参数预测食管癌术后早期并发症的价值。方法 回顾性分析184例食管癌根治术后患者,根据术后早期(术后30天内)是否发生并发症分为并发症组(n=76)与对照组(n=108)。基于L3椎体中心层面以QCT获得腹背部脂肪含量相关参数,包括内脏脂肪面积(VFA)、皮下脂肪面积(SFA)、VFA/SFA及椎后肌群脂肪浸润(MFI)程度;以单因素分析及多因素logistic回归分析临床、病理资料及腹背部脂肪含量相关QCT参数,筛选食管癌术后早期并发症的独立危险因素。绘制受试者工作特征(ROC)曲线,计算曲线下面积(AUC),评估单一独立危险因素及其联合预测效能。结果 VFA/SFA及椎后肌群MFI程度均为食管癌术后早期并发症的独立危险因素(OR=5.121、1.110,P均＜0.05),其AUC分别为0.81及0.77,二者联合AUC为0.84。结论 腹背部脂肪含量相关QCT参数可有效预测食管癌术后早期并发症。 |
| 英文摘要: |
| Objective To investigate the value of quantitative CT (QCT) parameters related to abdominal and dorsal fat content for predicting early postoperative complications of esophageal cancer. Methods A total of 184 patients who underwent radical esophageal cancer surgery were retrospectively collected and divided into complication group (n=76) and control group (n=108) according to whether early postoperation complication (within 30 days after surgery) occurred or not. QCT was used to obtain parameters related to abdominal and dorsal fat content, including visceral fat area (VFA), subcutaneous fat area (SFA), VFA/SFA and the degree of muscle fat infiltration (MFI) of posterior vertebral muscles based on L3 central-level CT images. Univariate analysis and multivariate logistic regression were used to analyze clinical and pathological data as well as QCT parameters related to abdominal and dorsal fat content to screen independent risk factors for early postoperative complications of esophageal cancer. Then receiver operating characteristic (ROC) curve was drawn, and the area under the curve (AUC) was calculated to evaluate the efficacy of each independent risk factor alone and their combination for predicting early postoperative complications of esophageal cancer. Results VFA/SFA and MFI degree of posterior vertebral muscles were both independent risk factors for early postoperative complications of esophageal cancer (OR=5.121, 1.110, both P＜0.05). The AUC of VFA/SFA and MFI degree of posterior vertebral muscle was 0.81 and 0.77, respectively, while of their combination was 0.84. Conclusion QCT parameters related to abdominal and dorsal fat content could be used to effectively predict early complications of esophageal cancer after surgery. |
| 查看全文 查看/发表评论 下载PDF阅读器 |
|
|
|
