| 伍雪,舒健,李品雄,闵凡.非酒精性脂肪性肝病患者定量非对称回波最小二乘估算法迭代水脂分离序列脂肪参数与临床资料的相关性[J].中国医学影像技术,2024,40(11):1715~1719 |
| 非酒精性脂肪性肝病患者定量非对称回波最小二乘估算法迭代水脂分离序列脂肪参数与临床资料的相关性 |
| Correlations of iterative decomposition of water and fat with echo asymmetry and the least squares estimation quantification sequence fat parameters and clinical data in patients with non-alcoholic fatty liver disease |
| 投稿时间：2024-04-14 修订日期：2024-09-05 |
| DOI：10.13929/j.issn.1003-3289.2024.11.017 |
| 中文关键词: 非酒精性脂肪肝 脂肪组织 磁共振成像 水脂分离 |
| 英文关键词:non-alcoholic fatty liver disease adipose tissue magnetic resonance imaging water-fat separation |
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| 中文摘要: |
| 目的 观察非酒精性脂肪性肝病(NAFLD)定量非对称回波最小二乘估算法迭代水脂分离序列(IDEAL-IQ)脂肪参数与临床资料的相关性。方法 前瞻性纳入42例NAFLD患者,根据体质量指数分为瘦型组(n=9)、超重组(n=19)及肥胖组(n=14);比较3组间及两两组间临床资料及IDEAL-IQ脂肪参数,分析HFF、腹部VAT及SAT体积与临床资料的相关性。结果 3组腹部VAT及SAT体积差异均有统计学意义(P均＜0.05);其中,肥胖组腹部VAT体积明显高于瘦型组及超重组,两两组间比较腹部SAT体积差异均有统计学意义(P均＜0.05)。男性与女性患者腹部VAT及SAT体积差异均有统计学意义(t=2.559、－2.606,P均＜0.05),而HFF差异无统计学意义(t=1.332,P=0.191)。NAFLD患者HFF与年龄、收缩压(SBP)、舒张压(DBP)及谷草转氨酶(GOT)均呈正相关(r=0.418、0.408、0.370、0.340,P均＜0.05)。结论 NAFLD患者HFF与年龄、SBP、DBP及AST相关,腹部VAT及SAT体积与性别相关。 |
| 英文摘要: |
| Objective To observe the correlations of iterative decomposition of water and fat with echo asymmetry and the least squares estimation quantification sequence (IDEAL-IQ) fat parameters and clinical data in patients with non-alcoholic fatty liver disease (NAFLD). Methods Totally 42 NAFLD patients were prospectively enrolled and divided into lean group (n=9), overweight group (n=19) and obese group (n=14) based on body mass index. Clinical data and IDEAL-IQ fat parameters (hepatic fat fraction, abdominal visceral adipose tissue and subcutaneous adipose tissue volumes) were compared among 3 groups and between each 2 groups, and the correlations of HFF, abdominal VAT and SAT volumes and clinical data were analyzed. Results Significant differences of abdominal VAT and SAT volumes were found among 3 groups (both P＜0.05). Abdominal VAT volume in obese group was significantly higher than that in lean and overweight groups (both P＜0.05), and significant differences of abdominal SAT volume were found between each 2 groups (all P＜0.05). Meanwhile, significant differences of abdominal VAT and SAT volumes were found between male and female patients (t=2.559, -2.606, both P＜0.05), but not of HFF (t=1.332, P=0.191). HFF was positively correlated with age, systolic blood pressure (SBP), diastolic blood pressure (DBP) and glutamic-oxaloacetic transaminase (GOT) in NAFLD patients (r=0.418, 0.408, 0.370, 0.340, all P＜0.05). Conclusion In NAFLD patients, HFF was related to age, SBP, DBP and GOT, while abdominal VAT and SAT volumes were related to gender. |
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