| 吴家昊,李春,刘志兴,刘旮,吕佳杰.微波消融治疗继发性甲状旁腺功能亢进症后早期低钙血症的影响因素[J].中国医学影像技术,2024,40(9):1327~1331 |
| 微波消融治疗继发性甲状旁腺功能亢进症后早期低钙血症的影响因素 |
| Influencing factors of early hypocalcemia after microwave ablation for treating secondary hyperparathyroidism |
| 投稿时间：2024-01-18 修订日期：2024-04-11 |
| DOI：10.13929/j.issn.1003-3289.2024.09.011 |
| 中文关键词: 甲状旁腺功能亢进症,继发性 低钙血症 消融技术 超声检查 |
| 英文关键词:hyperparathyroidism, secondary hypocalcemia ablation techniques ultrasonography |
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| 中文摘要: |
| 目的 观察微波消融(MWA)治疗继发性甲状旁腺功能亢进症(SHPT)后早期低钙血症的影响因素。方法 回顾性分析82例接受MWA治疗的SHPT患者,根据MWA后早期有无低钙血症将其分为低钙组(n=36)与非低钙组(n=46)。比较组间患者年龄、性别、体质量指数(BMI)、透析方式、透析时间、病灶数目,以及基线血钙、血磷、全段甲状旁腺激素(iPTH)、碱性磷酸酶(ALP)、血红蛋白、白蛋白、肌酐、尿素、25-羟维生素D3;行logistic分析,筛选MWA后早期低钙血症的影响因素。结果 组间透析方式、病灶数目、血钙、iPTH及ALP差异均有统计学意义(P均＜0.05)。单因素及多因素logistic回归分析结果显示,病灶数目、iPTH及ALP为MWA治疗SHPT后早期低钙血症的独立影响因素(P均＜0.05)。结论 病灶数目、iPTH及ALP为MWA治疗SHPT后早期低钙血症的影响因素。 |
| 英文摘要: |
| Objective To observe the influencing factors of early hypocalcemia after microwave ablation (MWA) for treating secondary hyperparathyroidism (SHPT). Methods Data of 82 SHPT patients who underwent MWA were retrospectively analyzed. The patients were divided into hypocalcemia group (n=36) and non-hypocalcemia group (n=46) based on presence of early hypocalcemia after MWA or not. Patients' age, gender, body mass index (BMI), dialysis method, dialysis time and number of lesions were compared between groups, so were baseline blood calcium, blood phosphorus, intact parathyroid hormone (iPTH), alkaline phosphatase (ALP), hemoglobin, albumin, creatinine, uric acid and 25-hydroxyvitamin D3. Logistic analysis was performed to screen the influencing factors of early hypocalcemia after MWA. Results Significant differences of dialysis methods, number of lesions, blood calcium, iPTH and ALP were found between groups (all P＜0.05). Univariate and multivariate logistic regression analysis showed that the number of lesions, iPTH and ALP were all independent influencing factors of early hypocalcemia after MWA for treating SHPT (all P＜0.05). Conclusion The number of lesions, iPTH and ALP were influencing factors of early hypocalcemia after MWA for treating SHPT. |
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