| 郑德春,许淑桂,赖国静,胡春淼,曹喜生,冯妹妹,彭莉.各向同性容积MRI显示鼻咽癌脑神经周围扩散[J].中国医学影像技术,2024,40(8):1164~1169 |
| 各向同性容积MRI显示鼻咽癌脑神经周围扩散 |
| Isotropic volumetric MRI for displaying cranial perineural spread of cranial nerve in nasopharyngeal carcinoma |
| 投稿时间：2024-01-11 修订日期：2024-03-21 |
| DOI：10.13929/j.issn.1003-3289.2024.08.010 |
| 中文关键词: 鼻咽肿瘤 脑神经 磁共振成像 肿瘤转移 前瞻性研究 |
| 英文关键词:nasopharyngeal neoplasm cranial nerve magnetic resonance imaging neoplasm metastasis prospective studies |
| 基金项目:福建省自然基金项目(2021J01427)。 |
|
| 摘要点击次数: 885 |
| 全文下载次数: 729 |
| 中文摘要: |
| 目的 观察各向同性容积MRI显示鼻咽癌脑神经(CN)周围扩散(PNS)的价值。方法 前瞻性纳入87例经病理证实的鼻咽癌患者,采集鼻咽及颈部各向同性三维肝脏容积加速采集(3D LAVA_Flex)序列图像、脂肪抑制T2WI(T2WI-FS)、T1WI及增强T1WI-FS,分别于患者水平、CN组水平及单支神经水平比较各序列显示鼻咽癌CN PNS的价值。结果 对于鼻咽癌CN PNS,3D LAVA_Flex序列阳性率为49.43%(43/87),高于常规MRI的34.48%(30/87,P=0.001)。在59例常规序列诊断为中晚期鼻咽癌患者中,3D LAVA_Flex序列显示CN PNS的阳性率为71.19%(42/59),常规MRI为50.85%(30/59),前者高于后者(P=0.001);在患者及后组CN水平,3D LAVA_Flex序列与T2WI-FS、T1WI、增强T1WI-FS显示CN PNS阳性率差异均有统计学意义(P均＜0.05);而在单支CN水平,3D LAVA_Flex序列显示下颌神经、颈静脉孔CN Ⅸ~Ⅺ、颈动脉鞘间隙CN Ⅸ~Ⅻ PNS的阳性率均高于T2WI-FS、T1WI及增强T1WI-FS(P均＜0.05),显示海绵窦CN Ⅲ~Ⅴ PNS的阳性率高于T2WI-FS(P＜0.05),显示舌下神经PNS阳性率高于T2WI-FS及T1WI(P均＜0.05)。结论 3D LAVA_Flex序列可较好地显示鼻咽癌CN PNS。 |
| 英文摘要: |
| Objective To observe the value of isotropic volumetric MRI for displaying perineural spread (PNS) of cranial nerve (CN) in nasopharyngeal carcinoma. Methods Eighty-seven patients with pathologically proven nasopharyngeal carcinoma were prospectively enrolled. MR scanning, including three-dimensional liver acquisition with volume acceleration-flexible (3D LAVA_Flex) image, T2WI with fat suppression (T2WI-FS), T1WI, contrast enhancement (CE) T1WI-FS of nasopharynx and neck region were performed. The displaying rates of CN PNS were evaluated and compared between 3D LAVA_Flex and T2WI-FS, T1WI, CE-T1WI-FS at patient level, CN group level and neural level, respectively. Results The displaying rate of CN PNS in all 87 nasopharyngeal carcinoma patients by 3D LAVA_Flex sequence was 49.43% (43/87), higher than that of conventional MRI (30/87, 34.48%, P=0.001). Among 59 patients with advanced nasopharyngeal carcinoma diagnosed with conventional sequences, the displaying rate of CN PNS was 71.19% (42/59) by 3D LAVA-Flex sequence, higher than that of conventional MRI (30/59, 50.85%, P=0.001). At both patient level and posterior CN level, significant differences of the displaying rate of CN PNS were found between 3D LAVA-Flex sequence and T2WI-FS, T1WI, CE-T1WI-FS, while at CN level, the displaying rates of mandibular nerve PNS, CN Ⅸ—Ⅺ PNS in jugular foramen (P＜0.05) and CN Ⅸ—Ⅻ PNS in carotid space of 3D LAVA_Flex sequence were all significantly higher than that of T2WI-FS, T1WI and CE-T1WI-FS (all P＜0.05), of PNS of CN Ⅲ—Ⅴ in cavernous sinus were higher than that of T2WI-FS (P＜0.05), while of PNS of hypoglossal nerve were significantly higher than that of T2WI-FS and T1WI (both P＜0.05). Conclusion 3D LAVA_Flex sequence could be used to effectively display CN PNS of nasopharyngeal carcinoma. |
| 查看全文 查看/发表评论 下载PDF阅读器 |
|
|
|
