| 林学智,张国建.68Ga-FAPI PET显像用于心血管疾病研究进展[J].中国医学影像技术,2024,40(7):1096~1099 |
| 68Ga-FAPI PET显像用于心血管疾病研究进展 |
| Research progresses of 68Ga-FAPI PET imaging in cardiovascular diseases |
| 投稿时间：2023-12-19 修订日期：2024-03-19 |
| DOI：10.13929/j.issn.1003-3289.2024.07.028 |
| 中文关键词: 成纤维细胞激活蛋白α 心血管疾病 正电子发射断层显像 |
| 英文关键词:fibroblast activation protein alpha cardiovascular disease positron-emission tomography |
| 基金项目:内蒙古科技成果转化专项(2019CG097)。 |
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| 中文摘要: |
| 心肌纤维化与多种心血管疾病(CVD)发生、发展密切相关,而成纤维细胞激活蛋白(FAP)在其中发挥关键作用。68Ga-FAP抑制剂(FAPI)对FAP具有高亲和力及特异度,现已逐渐用于心血管PET显像。本文围绕68Ga-FAPI PET显像用于CVD研究进展进行综述。 |
| 英文摘要: |
| Myocardial fibrosis is closely related to the occurrence and development of various cardiovascular diseases (CVD), in which fibroblast activation protein (FAP) plays key roles. 68Ga-FAP inhibitors (FAPI) have high affinity and specificity for FAP, having been gradually applied to cardiovascular PET imaging. The research progresses of 68Ga-FAPI PET imaging in cardiovascular diseases were reviewed in this article. |
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