| 刘建宪,王振松,王鑫,田宁,陈鹏,于丹,杨燕兴,程传力,邹超,甘洁.基于5.0T MRI定量肝脏质子密度脂肪分数[J].中国医学影像技术,2024,40(5):671~676 |
| 基于5.0T MRI定量肝脏质子密度脂肪分数 |
| 5.0T MRI for quantifying proton density fat fraction of liver |
| 投稿时间：2024-01-11 修订日期：2024-03-10 |
| DOI：10.13929/j.issn.1003-3289.2024.05.008 |
| 中文关键词: 肝 脂肪组织 磁共振成像 脂肪分数 前瞻性研究 |
| 英文关键词:liver adipose tissue magnetic resonance imaging fat fraction prospective studies |
| 基金项目:山东省医药卫生科技项目(202209010957)。 |
| 作者 | 单位 | E-mail | | 刘建宪 | 山东大学附属山东省立第三医院影像中心, 山东 济南 250032 | | | 王振松 | 山东大学附属山东省立第三医院影像中心, 山东 济南 250032 | | | 王鑫 | 山东大学附属山东省立第三医院影像中心, 山东 济南 250032 | | | 田宁 | 山东大学附属山东省立第三医院影像中心, 山东 济南 250032 | | | 陈鹏 | 山东大学附属山东省立第三医院影像中心, 山东 济南 250032 | | | 于丹 | 北京联影智能影像技术研究院, 北京 100094 | | | 杨燕兴 | 上海联影医疗科技股份有限公司, 上海 201807 | | | 程传力 | 深圳先进技术研究院劳特伯生物医学成像研究中心, 广东 深圳 518055 | | | 邹超 | 深圳先进技术研究院劳特伯生物医学成像研究中心, 广东 深圳 518055 | | | 甘洁 | 山东大学附属山东省立第三医院影像中心, 山东 济南 250032 | ganjie000@sina.com |
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| 中文摘要: |
| 目的 观察5.0T MRI用于定量肝脏质子密度脂肪分数(PDFF)的价值。方法 前瞻性对30名受试者分别行5.0T、3.0T、1.5T 肝脏化学位移编码(CSE)MR扫描,测量CSE-PDFF;之后行5.0T、1.5T MR波谱(MRS),测量MRS-PDFF。分析不同方法所测肝脏PDFF的一致性,评估5.0T MRI定量肝脏PDFF的价值。结果 以不同场强MR设备所测肝脏CSE-PDFF总体一致性良好(ICC均＞0.75,P均＜0.001);基于5.0T MR与3.0T、1.5T MR所测肝脏CSE-PDFF的一致性均好(ICC=0.989、0.992,P均＜0.001)。基于5.0T MR所测CSE-PDFF与5.0T、1.5T MR所测MRS-PDFF一致性均好(ICC均＞0.75,P均＜0.001);其中,5.0T MR所测CSE-PDFF与MRS-PDFF一致性好(ICC=0.988,P＜0.001),5.0T MR所测CSE-PDFF与1.5T MR所测MRS-PDFF一致性好(ICC=0.978,P＜0.001)。结论 5.0T MRI对定量肝脏PDFF具有较高价值。 |
| 英文摘要: |
| Objective To observe the value of 5.0T MRI for quantifying proton density fat fraction (PDFF) of liver. Methods Liver chemical shift encoded (CSE) MR scanning were prospectively performed using 5.0T, 3.0T and 1.5T scanner in 30 volunteers, respectively, and CSE-PDFF were measured. Then MR spectroscopy (MRS) were performed using 5.0T and 1.5T scanner, respectively, and MRS-PDFF were also measured. The consistency of liver PDFF measured on different images was observed, and the value of 5.0T MRI for liver PDFF was analyzed. Results The overall consistencies of liver CSE-PDFF measured with 5.0T, 3.0T and 1.5T MR scanner were all good (all ICC＞0.75, all P＜0.001). The consistency of liver CSE-PDFF based on 5.0T and 3.0T, 1.5T MR scanner were both good (ICC=0.989, 0.992, both P＜0.001). The overall consistencies of CSE-PDFF based on 5.0T MR and MRS-PDFF based on 5.0T and 1.5T MR were both good (both ICC＞0.75, both P＜0.001). CSE-PDFF had good consistency with MRS-PDFF based on same 5.0T MR scanner (ICC=0.988, P＜0.001), and CSE-PDFF based on 5.0T had good consistency with MRS-PDFF based on 1.5T MR scanner (ICC=0.978, P＜0.001). Conclusion 5.0T MRI had high value for quantifying liver PDFF. |
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