| 刘莎莎,于双得,贾海鹏,张宏波.三代双源CT Sn 100 kVp能谱纯化成像用于引导经皮穿刺肺活检[J].中国医学影像技术,2024,40(4):609~613 |
| 三代双源CT Sn 100 kVp能谱纯化成像用于引导经皮穿刺肺活检 |
| The third-generation dual-source CT Sn 100 kVp scanning for guiding percutaneous core needle biopsy of pulmonary nodules |
| 投稿时间：2023-10-04 修订日期：2024-01-12 |
| DOI：10.13929/j.issn.1003-3289.2024.04.028 |
| 中文关键词: 孤立性肺结节 活组织检查 体层摄影术,X线计算机 前瞻性研究 |
| 英文关键词:solitary pulmonary nodule biopsy tomography, X-ray computed prospective studies |
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| 中文摘要: |
| 目的 观察三代双源CT Sn 100 kVp能谱纯化成像引导经皮穿刺肺活检的效能、安全性及辐射剂量。方法 前瞻性随机将210例孤立性肺结节穿刺患者分入超低剂量CT(ULDCT)组(100例,以Sn 100 kVp、70 mAs超低剂量能谱纯化技术CT引导肺穿刺活检)或常规标准剂量CT(SDCT)组(110例,以110 kVp、50 mAs常规标准剂量CT引导肺穿刺活检),比较2组肺结节穿刺活检取材成功率、诊断效能、并发症发生率、图像质量及辐射剂量。结果 ULDCT组穿刺活检取材成功率为97.00%,与SDCT组(98.18%)差异无统计学意义 (P＞0.05)。组间取材成功后诊断敏感度、特异度、准确率及并发症发生率差异均无统计学意义(P均＞0.05)。相比SDCT组,ULDCT组用于引导穿刺活检的平均CT扫描范围差异无统计学意义(P=0.520),而平均容积CT剂量指数、总剂量长度乘积及有效剂量均有所降低(P均＜0.05);且ULDCT组图像质量可满足穿刺活检需要。结论 三代双源CT超低剂量Sn 100 kVp能谱纯化成像用于引导经皮穿刺肺活检可在保证诊断成功率及安全性的同时降低辐射剂量。 |
| 英文摘要: |
| Objective To observe the efficacy, safety and radiation dose of the third generation dual-source CT Sn 100 kVp scanning for guiding percutaneous needle biopsy of pulmonary nodules. Methods Totally 210 patients with solitary pulmonary nodule were prospectively enrolled and randomly assigned into ultra-low-dose CT group (ULDCT, n=100, underwent CT guidance of Sn 100 kVp and 70 mAs scanning) or standard-dose CT group (SDCT, n=110, underwent CT guidance of 110 kVp and 50 mAs scanning). The successful rate of sampling, diagnostic efficacy, incidence of complications, imaging qualities and radiation doses were compared between groups. Results The success sampling and biopsy rate in ULDCT group was 97.00%, not significantly different with that in SDCT group (98.18%, P＞0.05). No significant difference of diagnostic sensitivity, specificity, accuracy of biopsy after successful sampling nor incidence of complication was detected between groups (all P＞0.05). Compared with those in SDCT group, ULDCT group had undifferentiated mean CT scan range (P=0.520) but lower mean volume CT dose index, total dose-length product and effective dose (all P＜0.05), and imaging qualities of ULDCT met the requirements of percutaneous needle biopsy. Conclusion Using the third-generation dual-source CT Sn 100 kVp scanning could simultaneously ensure the diagnostic accuracy and safety of percutaneous needle lung biopsy and significantly reduce radiation dose. |
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