| 祝安惠,侯小艳,张卫方.18F-FDG PET/CT诊断肾细胞癌伴下腔静脉癌栓侵犯下腔静脉壁[J].中国医学影像技术,2024,40(4):580~584 |
| 18F-FDG PET/CT诊断肾细胞癌伴下腔静脉癌栓侵犯下腔静脉壁 |
| 18F-FDG PET/CT for diagnosing renal cell carcinoma complicated with inferior vena cava tumor thrombi involving inferior vena cava wall |
| 投稿时间：2023-11-06 修订日期：2024-01-07 |
| DOI：10.13929/j.issn.1003-3289.2024.04.022 |
| 中文关键词: 肾肿瘤 腔静脉,下 体层摄影术,X线计算机 正电子发射断层显像 |
| 英文关键词:kidney neoplasms vena cava, inferior tomography, X-ray computed positron-emission tomography |
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| 中文摘要: |
| 目的 观察18F-FDG PET/CT诊断肾细胞癌(RCC)伴下腔静脉(IVC)癌栓侵犯IVC壁的价值。方法 回顾性分析71例接受手术治疗的RCC伴IVC癌栓患者,根据癌栓是否侵犯IVC壁分为侵犯组(n=40)及无侵犯组(n=31);比较组间一般资料和PET/CT特征,分析各指标诊断癌栓侵犯IVC壁的效能。结果 组间原发灶最大标准摄取值(SUVmax)、癌栓比、癌栓最大横径、长径,以及病理类型差异均有统计学意义(P均＜0.05)。癌栓比和癌栓最大横径为RCC伴IVC癌栓侵犯IVC壁的影响因素(P均＜0.05)。以1.33为最佳截断值,根据癌栓比诊断RCC伴IVC癌栓侵犯IVC壁的敏感度为47.50%,特异度为87.10%, AUC为0.70;以3.45 cm为最佳截断值,根据癌栓最大横径诊断的敏感度为65.00%,特异度为87.10%,AUC为0.81;二者联合诊断敏感度为90.00%,特异度为77.40%,AUC为0.86。结论 以18F-FDG PET/CT所获癌栓比及癌栓最大横径可用于术前诊断RCC伴IVC癌栓侵犯IVC壁。 |
| 英文摘要: |
| Objective To observe the value of 18F-FDG PET/CT for diagnosing renal cell carcinoma (RCC) complicated with inferior vena cava (IVC) tumor thrombi involving IVC wall. Methods Data of 71 patients with RCC complicated with IVC tumor thrombi who underwent surgical treatment were retrospectively analyzed. The patients were divided into invasion group (n=40) or non-invasion group (n=31) based on whether tumor thrombi involved IVC wall. General information and PET/CT features were compared between groups, and the efficiency of each parameter for diagnosing tumor thrombi involving IVC wall was evaluated. Results There were significant differences of the maximum standard uptake value (SUVmax), tumor thrombi ratio, the maximum transverse diameter and length as well as pathological type between groups (all P＜0.05). Tumor thrombi ratio and the maximum transverse diameter were impact factors of RCC complicated with IVC tumor thrombi involving IVC wall (both P＜0.05). Taken 1.33 as the best cutoff value, the sensitivity, specificity and area under the curve (AUC) of tumor thrombi ratio for diagnosing RCC complicated with IVC tumor thrombi involving IVC wall was 47.50%, 87.10% and 0.70, respectively, while taken 3.45 cm as the best cutoff value of tumor thrombi maximum transverse diameter, the sensitivity, specificity and AUC was 65.00%, 87.10% and 0.81, respectively. The sensitivity, specificity and AUC of the combination diagnosis of the above two was 90.00%, 77.40% and 0.86, respectively. Conclusion Tumor thrombi ratio and the maximum transverse diameter of tumor obtained with 18F-FDG PET/CT could be used for preoperative diagnosis of RCC complicated with IVC tumor thrombi involved IVC wall. |
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