| 潘璐,黄璇,王婷婷,纳丽莎.超声心动图评价系统性红斑狼疮伴肺动脉高压患者右心室-肺动脉耦联[J].中国医学影像技术,2024,40(4):531~535 |
| 超声心动图评价系统性红斑狼疮伴肺动脉高压患者右心室-肺动脉耦联 |
| Echocardiographic evaluation of right ventricle-pulmonary artery coupling in systemic lupus erythematosus patients combined with pulmonary hypertension |
| 投稿时间：2023-10-17 修订日期：2023-12-20 |
| DOI：10.13929/j.issn.1003-3289.2024.04.011 |
| 中文关键词: 红斑狼疮,系统性 心室功能,右 超声心动描记术 导管插入术,Swan-Ganz |
| 英文关键词:lupus erythematosus, systemic ventricular function, right echocardiography catheterization, Swan-Ganz |
| 基金项目:宁夏回族自治区卫生健康系统科研课题(2022-NWKY-60)。 |
|
| 摘要点击次数: 850 |
| 全文下载次数: 571 |
| 中文摘要: |
| 目的 以超声心动图观察不同肺动脉压系统性红斑狼疮(SLE)患者心脏功能改变,分析右心室-肺动脉(RV-PA)耦联参数与右心室功能及肺动脉平均压(mPAP)的相关性。方法 回顾性分析69例SLE患者,根据三尖瓣反流速度(TRV)及有无肺动脉高压(PAH),将其分为无PAH 的A组(TRV≤2.8 m/s)及B组(TRV＞2.8 m/s),将存在PAH者纳入C组(mPAP≥25 mmHg)。根据二维经胸超声心动图及实时三维超声心动图所见,对比各组右心径线和右心室容量、左心室和右心室收缩及舒张功能、三尖瓣环收缩期位移/肺动脉收缩压(TAPSE/PASP),分析TAPSE/PASP与右心室功能及mPAP的相关性。结果 相比A组,C组右心增大,B、C组右心室容量增加(校正P均＜0.05)。A、B、C组之间,右心室收缩功能逐渐减低,B、C组右心室舒张功能低于A组(校正P均＜0.05);3组左心室收缩及舒张功能差异均无统计学意义(P均＞0.05)。全部69例TAPSE/PASP与右心室舒张末期容积呈负相关(rs=－0.420,P＜0.001)、与右心室射血分数呈正相关(rs=0.584,P＜0.001);C组TAPSE/PASP与mPAP呈负相关(rs=－0.539,P=0.012)。结论 SLE伴肺动脉压升高患者可存在右心室功能降低;TAPSE/PASP与右心室收缩、舒张功能及mPAP相关。 |
| 英文摘要: |
| Objective To observe changes of cardiac function in systemic lupus erythematosus (SLE) patients with different pulmonary artery pressure, and to explore correlations of right ventricle pulmonary artery (RV-PA) coupling parameters with right ventricular function and mean pulmonary artery pressure (mPAP). Methods Data of 69 SLE patients were retrospectively analyzed. According to tricuspid regurgitation velocity (TRV) and the presence or absence of pulmonary arterial hypertension (PAH), patients without PAH were categorized into group A (TRV≤2.8 m/s) or B (TRV＞2.8 m/s), while those with PAH into group C (mPAP≥25 mmHg). Two-dimensional transthoracic echocardiography and real-time three-dimensional echocardiography results were reviewed to comparatively observe right heart size and right ventricular volume, left and right ventricular systolic and diastolic function, as well as tricuspid annular systolic displacement/pulmonary artery systolic pressure (TAPSE/PASP) among groups, and correlations of TAPSE/PASP with changes of right ventricular function and mPAP were analyzed. Results Compared with group A, the right heart enlarged in group C, and the right ventricular volume increased in groups B and C (all adjusted P＜0.05). Right ventricular systolic function progressively reduced in groups A, B and C, while right ventricular diastolic function reduced in groups B and C compared with group A (all adjusted P＜0.05), but no significant difference of left ventricular systolic nor diastolic function was found among 3 groups (all P＞0.05). TAPSE/PASP was negatively correlated with right ventricular end diastolic volume (rs=－0.420, P＜0.001) and positively correlated with right ventricular ejection fraction (rs＝0.584, P＜0.001). TAPSE/PASP was negatively correlated with mPAP in group C (rs=－0.539, P=0.012). Conclusion SLE complicated with elevated pulmonary artery systolic pressure might have reduced right ventricular function, in whom TAPSE/PASP correlated with right ventricular systolic and diastolic function as well as mPAP. |
| 查看全文 查看/发表评论 下载PDF阅读器 |
|
|
|
