| 王阳,张晖,李洪兵,程令刚,杜凯,何文,张巍.微波消融猪乳腺的最佳模式[J].中国医学影像技术,2024,40(4):498~501 |
| 微波消融猪乳腺的最佳模式 |
| Optimal mode of microwave ablation for pig mammary glands |
| 投稿时间：2024-01-19 修订日期：2024-02-24 |
| DOI：10.13929/j.issn.1003-3289.2024.04.005 |
| 中文关键词: 猪 乳腺肿瘤 消融技术 超声检查 |
| 英文关键词:swine breast neoplasms ablation techniques ultrasonography |
| 基金项目:国家自然科学基金(82171935)、广西壮族自治区中医药管理局自筹经费科研课题(GXZYA20220358)。 |
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| 中文摘要: |
| 目的 观察对猪乳腺行微波消融(MWA)的最佳模式。方法 分别对4只猪以不同模式行MWA:模式1为约400 J能量+5 mm针型,模式2为约400 J能量+3 mm针型,模式3为约1 000 J能量+3 mm针型,模式4为约2 000 J能量+3 mm针型;比较不同模式下消融灶超声表现及病理特征(仅对模式2、3、4消融灶切开送病理)和消融致皮肤热损伤发生率。结果 MWA前及以模式1~4行MWA后,猪乳腺硬度差异均有统计学意义(F=50.281,P=0.009);MWA后乳腺硬度均明显高于MWA前(P均＜0.05),模式1消融灶硬度明显大于模式2~4(P均＜0.05)。超声造影显示消融灶长径为(21.24±3.68)mm,与大体标本所见差异无统计学意义(P=0.465);宽径为(9.43±1.50)mm,大于大体标本所见(P=0.001)。大体标本显示,模式2、3、4之间,消融灶长径差异具有统计学意义(P＜0.001)。以模式1行MWA后猪皮肤见3处红肿、1处水泡,以模式4行MWA后见3处红肿、2处水泡,模式2、3均未见皮肤热损伤;各模式间皮肤热损伤差异均有统计学意义(P均＜0.05)。结论 低能量+3 mm发射前端针型为MWA用于猪乳腺最佳模式。 |
| 英文摘要: |
| Objective To observe the optimal mode of microwave ablation (MWA) for pig mammary glands. Methods MWA of mammary glands were performed under different modes in 4 pigs, respectively. Mode 1 was about 400 J energy+5 mm needle type, mode 2 was about 400 J energy+3 mm needle type, mode 3 was about 1 000 J energy+3 mm needle type, and mode 4 was about 2 000 J energy+3 mm needle type. The ultrasonic characteristics and pathological findings (only for mode 2, 3 and 4) of ablated foci and the incidence of skin thermal injuries were compared among different modes of MWA. Results Significant differences of hardness of pig mammary glands were found before and after MWA under mode 1, 2, 3 and 4 (F=50.281, P=0.009), those after MWA were significantly higher than before (all P＜0.05), and under mode 1 were significantly higher than those under mode 2, 3 and 4 (all P＜0.05). The length of ablated foci on contrast-enhanced ultrasound (CEUS) was (21.24±3.68)mm, being not significantly different with that on the gross specimen (P=0.465), and the width was (9.43±1.50)mm, greater than that on the gross specimen (P=0.001). The length of ablated foci on the gross specimen after mode 2, 3 and 4 MWA were significantly different (P＜0.001). After mode 1 MWA, 3 areas of red and swollen and 1 area of blister were detected on the skin, after mode 4 MWA 3 areas of red and swollen and 2 areas of blisters were found, while no skin thermal damage was observed after mode 2 and 3 MWA. Significantly differences of skin thermal damages were found among different modes MWA (all P＜0.05). Conclusion Low energy+3 mm emission front needle was the optimal mode of MWA for pig mammary glands. |
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