赵博峰,郭笑寒,陈平,冯炜,魏东红,陈宝莹.CT“切缘征”鉴别直径<4 cm复杂胸腺囊肿与胸腺上皮肿瘤[J].中国医学影像技术,2023,39(12):1823~1826
CT“切缘征”鉴别直径<4 cm复杂胸腺囊肿与胸腺上皮肿瘤
CT “cut-edge sign” for differentiating complex thymic cyst and thymic epithelial tumor with diameter less than 4 cm
投稿时间:2023-09-19  修订日期:2023-11-09
DOI:10.13929/j.issn.1003-3289.2023.12.018
中文关键词:  纵隔囊肿  胸腺肿瘤  体层摄影术,X线计算机
英文关键词:mediastinal cyst  thymus neoplasms  tomography, X-ray computed
基金项目:西安国际医学中心医院院级课题青年项目(2022QN29)。
作者单位E-mail
赵博峰 西安国际医学中心医院影像诊疗中心, 陕西 西安 710700  
郭笑寒 西安国际医学中心医院影像诊疗中心, 陕西 西安 710700  
陈平 西安国际医学中心医院影像诊疗中心, 陕西 西安 710700  
冯炜 西安国际医学中心医院影像诊疗中心, 陕西 西安 710700  
魏东红 西安国际医学中心医院影像诊疗中心, 陕西 西安 710700  
陈宝莹 西安国际医学中心医院影像诊疗中心, 陕西 西安 710700 chenby128@163.com 
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中文摘要:
      目的 观察CT"切缘征"鉴别直径<4 cm复杂胸腺囊肿与胸腺上皮肿瘤(TET)的价值。方法 回顾性分析24例接受胸部CT平扫及双期增强扫描、并经手术病理证实的复杂胸腺囊肿(囊肿组)及14例TET (TET组)患者;由2名医师分别评估CT图像"切缘征",以组内相关系数(ICC)评价观察者间评估结果的一致性;采用logistic回归分析比较2组CT"切缘征"检出率;绘制受试者工作特征(ROC)曲线,计算曲线下面积(AUC),分析CT"切缘征"鉴别复杂胸腺囊肿与TET的效能。结果 观察者间评估"切缘征"结果的一致性良好[ICC=0.94,95%CI(0.90,0.97)]。囊肿组CT"切缘征"检出率为62.50%(15/24),高于TET组的14.29%(2/14,P<0.01)。以CT"切缘征"鉴别复杂胸腺囊肿与TET的敏感度、特异度、准确率及AUC分别为62.50%(15/24)、85.71%(12/14)、71.05%(27/38)及0.74。结论 CT"切缘征"有助于鉴别直径<4 cm复杂胸腺囊肿与TET。
英文摘要:
      Objective To observe the value of CT "cut-edge sign" for differentiating complex thymic cyst and thymic epithelial tumor (TET) with diameter less than 4 cm. Methods Data of 24 patients with complex thymic cyst (complex thymic cyst group) and 14 patients with TET (TET group) confirmed by surgical pathology who underwent plain and dual-phase enhanced chest CT scanning were retrospectively analyzed. CT "cut-edge sign" was evaluated by 2 physicians, and the inter-observer consistency was evaluated using intra-class correlation coefficient (ICC). The detection rate of CT "cut-edge sign" was compared between groups using logistic regression analysis. Receiver operating characteristic (ROC) curve was drawn, and the area under the curve (AUC) was calculated to evaluate the efficacy of CT "cut-edge sign" for differentiating complex thymic cyst and TET. Results The inter-observer consistency of CT "cut-edge sign" was good (ICC=0.94, 95%CI [0.90, 0.97]). The detection rate of CT "cut-edge sign" in complex thymic cyst group was 62.50% (15/24), higher than in TET group (2/14,14.29%) (P<0.01). The sensitivity, specificity, accuracy and AUC of CT "cut-edge sign" for differentiating complex thymic cyst and TET was 62.50% (15/24), 85.71% (12/14), 71.05% (27/38) and 0.74, respectively. Conclusion CT "cut-edge sign" was helpful for differentiating complex thymic cyst and TET with diameter less than 4 cm.
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