| 宋文静,蒋雪,邢光辉,叶庆桂,罗渝昆.微血流成像诊断猪闭合性肝创伤[J].中国医学影像技术,2023,39(12):1783~1786 |
| 微血流成像诊断猪闭合性肝创伤 |
| Micro flow imaging for diagnosing closed liver trauma in pigs |
| 投稿时间：2023-07-14 修订日期：2023-10-18 |
| DOI：10.13929/j.issn.1003-3289.2023.12.008 |
| 中文关键词: 猪 肝 创伤和损伤 超声检查 |
| 英文关键词:swine liver wounds and injuries ultrasonography |
| 基金项目: |
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| 中文摘要: |
| 目的 观察微血流成像（MFI）诊断猪闭合性肝创伤的价值。方法 采用自制撞击器对全麻状态下的15只健康猪撞击其肝脏部位建立闭合性肝创伤猪模型；之后分别以常规超声、MFI及超声造影（CEUS）观察撞击后肝脏损伤部位、范围及程度；最后处死动物并取出肝脏，根据所见评估MFI诊断猪闭合性肝创伤的效能。结果 大体病理显示，撞击共对15只猪造成29处肝创伤。常规超声、MFI及CEUS诊断猪闭合性肝创伤的准确率分别为37.93%（11/29）、82.76%（24/29）及96.55%（28/29），常规超声与MFI及CEUS差异均有统计学意义（P均<0.05），而MFI与CEUS差异无统计学意义（P>0.05）。MFI于多数猪肝创伤处未见明显血流信号，于1只创伤处显示"泉涌状"、5只显示散在血流信号。CEUS中，15只猪肝创伤处均表现为低或无灌注区，1只损伤处造影剂呈"喷射状"、5只呈"泉涌状"自肝脏损伤部位溢出并于肝周或腹腔内形成液性暗区。结论 MFI对诊断猪闭合性肝损伤具有一定价值，可与CEUS相媲美。 |
| 英文摘要: |
| Objective To observe the value of micro flow imaging (MFI) for diagnosing closed liver trauma in pigs. Methods A self-made impactor was used to impact the liver of 15 healthy pigs under general anesthesia and establish pig models of closed liver trauma. Conventional ultrasound, MFI and contrast-enhanced ultrasound (CEUS) were used to observe the location, extent and degree of liver trauma. Afterwards, the pigs were executed and the livers were removed, and the liver lesions were observed. According gross pathological findings, the diagnostic efficacy of MFI was analyzed. Results Gross pathology showed a total of 29 liver traumas in 15 pigs. The accuracy rate of conventional ultrasound, MFI and CEUS for diagnosing liver trauma in pigs was 37.93% (11/29), 82.76% (24/29) and 96.55% (28/29), respectively. Significant difference was found between conventional ultrasound and MFI, also between conventional ultrasound and CEUS (both P<0.05), but not between MFI and CEUS (P>0.05). MFI showed no obvious blood flow signal in more than half pig liver trauma sites, while showed "spring like" in 1 pig and scattered blood flow signals in 5 pigs. On CEUS, liver trauma sites in pigs present as low or no perfusion, while "jet like" contrast agent overflow from the liver was noticed in 1 pig and "spring like" contrast agent overflow in 5 pigs, forming liquid dark areas around the liver or in abdominal cavity. Conclusion MFI had certain value for diagnosing closed liver trauma in pigs, hence being comparable to CEUS. |
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