| 郑璐,胡玉敬,张新超,田丛娜,李康,蔡晓雨,刘家乐,边艳珠.腰椎椎体99Tcm-MDP SPECT/CT定量代谢参数与患者一般资料的相关性[J].中国医学影像技术,2023,39(11):1706~1709 |
| 腰椎椎体99Tcm-MDP SPECT/CT定量代谢参数与患者一般资料的相关性 |
| Correlations of 99Tcm-MDP SPECT/CT quantitative metabolic parameters of lumbar vertebrae with patients' general data |
| 投稿时间：2023-08-14 修订日期：2023-10-19 |
| DOI：10.13929/j.issn.1003-3289.2023.11.025 |
| 中文关键词: 腰椎 体层摄影术,发射型计算机,单光子 前瞻性研究 |
| 英文关键词:lumbar vertebrae tomography, emission-computed, single-photon prospective studies |
| 基金项目: |
| 作者 | 单位 | E-mail | | 郑璐 | 河北省人民医院核医学科, 河北 石家庄 050051
河北省脑网络与认知障碍疾病重点实验室, 河北 石家庄 050051 | | | 胡玉敬 | 河北省人民医院核医学科, 河北 石家庄 050051 | | | 张新超 | 河北省人民医院核医学科, 河北 石家庄 050051 | | | 田丛娜 | 河北省人民医院核医学科, 河北 石家庄 050051 | | | 李康 | 河北省人民医院核医学科, 河北 石家庄 050051 | | | 蔡晓雨 | 河北省人民医院核医学科, 河北 石家庄 050051 | | | 刘家乐 | 河北省人民医院核医学科, 河北 石家庄 050051 | | | 边艳珠 | 河北省人民医院核医学科, 河北 石家庄 050051
河北省脑网络与认知障碍疾病重点实验室, 河北 石家庄 050051 | yanzhubian99@163.com |
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| 中文摘要: |
| 目的 观察腰椎椎体99Tcm-亚甲基二膦酸盐(MDP)SPECT/CT定量代谢参数与患者一般资料的相关性。方法 前瞻性对45例(男22例、女23例)未累及腰椎的恶性肿瘤患者行全身骨显像及腰椎SPECT/CT,在SPECT/CT图中于腰椎处放置感兴趣区容积(VOI),获得最大标准摄取值(SUVmax)、平均标准摄取值(SUVmean)、骨代谢总体积(MBV)及骨摄取总量(TBU);采用Pearson相关性分析观察腰椎椎体代谢参数与患者一般资料,包括年龄、身高及体质量的相关性。结果 腰椎椎体SUVmax与患者身高、体质量及年龄均呈正相关(r=0.196、0.189、0.227,P均＜0.05);SUVmean与身高、年龄呈正相关(r=0.135、0.133,P均＜0.05),与体质量无明显相关性(P＞0.05);MBV(r=0.221、0.583、0.410)、TBU(r=0.205、0.441、0.280)与年龄、身高及体质量均呈正相关(P均＜0.05)。男性与女性腰椎椎体SUVmax、MBV及TBU差异均有统计学意义(P均＜0.05),而SUVmean差异无统计学意义(P＞0.05)。结论 腰椎椎体99Tcm-MDP SPECT/CT定量代谢参数与年龄、性别及体质量相关。 |
| 英文摘要: |
| Objective To observe the correlations of 99Tcm-methylene diphosphonate (MDP) SPECT/CT quantitative metabolic parameters of lumbar vertebrae with patients' general data. Methods A total of 45 malignant tumor patients (22 males and 23 females) without bone involvement were prospectively enrolled, and whole body bone imaging and lumbar spine SPECT/CT were performed. Based on SPECT/CT images, the volumes of interest (VOI) were placed on lumbar vertebrae, and the maximum standard uptake value (SUVmax), mean standard uptake value (SUVmean), metabolic bone volume (MBV) and total bone uptake (TBU) were measured. Pearson correlation analysis was used to observe the correlations of metabolic parameters of lumbar vertebrae with patients'general data, including age, height and body mass. Results SUVmax of lumbar vertebrae were positively correlated with height, body mass and age (r=0.196, 0.189, 0.227, all P＜0.05), while SUVmean were positively correlated with height and age (r=0.135, 0.133, both P＜0.05) but not significantly correlated with body mass (P＞0.05). MBV (r=0.221, 0.583, 0.410) and TBU (r=0.205, 0.441, 0.280) of lumbar vertebrae were all positively correlated with age, height and body mass (all P＜0.05). There were significant differences of SUVmax, MBV and TBU of lumbar vertebrae between males and females (all P＜0.05), but not of SUVmean(P＞0.05). Conclusion 99Tcm-MDP SPECT/CT quantitative metabolic parameters of lumbar vertebrae were related to patients' age, gender and body mass. |
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