| 翟爱国,杨豪,朱百奇,彭雪华,邵剑波.儿童颅内占位伴中枢性性早熟MRI表现[J].中国医学影像技术,2023,39(8):1139~1143 |
| 儿童颅内占位伴中枢性性早熟MRI表现 |
| MRI manifestations of intracranial space-occupying complicated with central precocious puberty in children |
| 投稿时间：2023-03-31 修订日期：2023-06-27 |
| DOI：10.13929/j.issn.1003-3289.2023.08.005 |
| 中文关键词: 儿童 青春期,早熟 中枢神经系统疾病 磁共振成像 |
| 英文关键词:child puberty, precocious central nervous system diseases magnetic resonance imaging |
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| 中文摘要: |
| 目的 观察儿童颅内占位伴中枢性性早熟(CPP)MRI表现。方法 回顾性分析8例颅内占位伴CPP患儿,包括下丘脑错构瘤(HH)4例、鞍上蛛网膜囊肿 2例、松果体区混合性生殖细胞肿瘤及鞍上颅咽管瘤各1例;观察其平扫、增强MRI,弥散加权成像(DWI)、动脉自旋标记(ASL)及MR波谱(MRS)表现。结果 4例HH表现为下丘脑区结节或肿块,其中3例呈T1WI、T2WI等信号,增强后均未见强化;1例较大病灶偏左侧呈不规则T1WI低信号及T2WI高信号,增强后为无强化低信号区;4例DWI均呈等信号;3例接受ASL检查,均表现为等或低灌注;2例接受MRS检查,均见N-乙酰天门冬氨酸峰降低。2例鞍上蛛网膜囊肿表现为鞍上池区囊状T1WI低信号、T2WI高信号,伴幕上脑积水。1例松果体区混合性生殖细胞肿瘤表现为松果体区混杂信号肿块伴脑积水,增强后不均匀强化,DWI呈等或高信号,ASL呈等或高灌注。1例鞍上颅咽管瘤表现为鞍上肿块T1WI及T2WI呈稍高信号,囊壁见等信号结节,增强后囊壁及结节均明显强化;DWI呈低信号、ASL呈低灌注。结论 儿童颅内占位伴CPP的MRI表现具有一定特征性。 |
| 英文摘要: |
| Objective To explore MRI manifestations of intracranial space-occupying complicated with central precocious puberty (CPP) in children. Methods Data of 8 children with intracranial space-occupying complicated with CPP were retrospectively analyzed, including 4 cases of hypothalamic hamartoma (HH), 2 cases of suprasellar arachnoid cyst, 1 case of mixed germ cell tumor in pineal gland region and 1 case of suprasellar craniopharyngioma, and the manifestations of lesions on plain and enhanced MRI, on diffusion weighted imaging (DWI), arterial spin labeling (ASL) and MR spectroscopy (MRS) were observed. Results Plain MRI showed nodular or lump like space-occupying mass in the hypothalamic region in all 4 cases of HH. Equal signals on T1WI and T2WI without enhancement were observed in 3 cases, while the rest larger lesion presented as irregular low T1WI and high T2WI signals on the left side and unreinforced low signal area after administration of contrast agents. All HH lesions (4/4) presented as equal signals on DWI, with equal or low perfusion on ASL (3/3) and decreased N-acetyl aspartate peak MRS (2/2). Suprasellar arachnoid cysts in 2 cases present as cystic lesions with low T1WI signals and high T2WI signals in the suprasellar cistern area, consistent with the signal of cerebrospinal fluid and accompanied by supratentorial hydrocephalus. One case of mixed germ cell tumor in pineal gland region presented as mixed signals mass with hydrocephalus in the pineal gland region and uneven enhancement, equal or high signal on DWI, and equal or high perfusion on ASL. One case of suprasellar craniopharyngioma present as slightly high signal mass on T1WI and T2WI with isosignal nodule on capsule wall, low signal on DWI and low perfusion on ASL. On enhanced MRI, significant enhancement of capsule wall and nodule were noticed. Conclusion MRI manifestations of intracranial space-occupying complicated with CPP in children were characteristic on some degree. |
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