| 刘佳,孟令萃,李旻颖,黄键澎,符文彬,张建兴,周鹏.剪切波弹性成像评估针灸治疗改善帕金森病肌强直效果[J].中国医学影像技术,2023,39(7):1065~1069 |
| 剪切波弹性成像评估针灸治疗改善帕金森病肌强直效果 |
| Shear wave elastography for evaluating effect of acupuncture and moxibustion for improving myotonia caused by Parkinson disease |
| 投稿时间：2023-03-11 修订日期：2023-05-27 |
| DOI：10.13929/j.issn.1003-3289.2023.07.026 |
| 中文关键词: 帕金森病 针灸 超声检查 前瞻性研究 |
| 英文关键词:Parkinson disease acupuncture and moxibustion ultrasonography prospective studies |
| 基金项目:深圳市宝安区针灸临床研究中心项目(BAZJ2018239)、深圳市政府"医疗卫生三名工程"项目(SZSM201806077)、广东省中医药局科研项目(20221169)。 |
| 作者 | 单位 | E-mail | | 刘佳 | 广州中医药大学第二附属医院超声科, 广东 广州 510120 | | | 孟令萃 | 广州中医药大学第二附属医院超声科, 广东 广州 510120 | | | 李旻颖 | 广州中医药大学第二附属医院超声科, 广东 广州 510120 | | | 黄键澎 | 广州中医药大学第二附属医院超声科, 广东 广州 510120 | | | 符文彬 | 广州中医药大学第二附属医院超声科, 广东 广州 510120
广州中医药大学第二附属医院针灸科, 广东 广州 510120
深圳市宝安区针灸临床研究中心针灸科, 广东 深圳 518101 | | | 张建兴 | 广州中医药大学第二附属医院超声科, 广东 广州 510120 | | | 周鹏 | 深圳市宝安区针灸临床研究中心针灸科, 广东 深圳 518101
广州中医药大学第七临床医学院 深圳市宝安中医院(集团)针灸科, 广东 深圳 518101 | zpmm1999@163.com |
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| 中文摘要: |
| 目的 观察剪切波弹性成像(SWE)评价针灸治疗帕金森病(PD)改善肌强直效果的价值。方法 前瞻性纳入60例PD患者并随机分为针灸组(AM组)和对照组,以"从阳论治"方案治疗针灸组,对照组予以安慰针;比较组间及组内治疗前、治疗第6周及完成治疗后肱二头肌、肱桡肌、股直肌、小腿三头肌SWE值,以及统一PD评分量表(UPDRS)Ⅲ评分的差异及其相关性。结果 AM组28例、对照组24例共52例治疗有效。治疗前股直肌SWE值组间差异有统计学意义(P<0.05);治疗前及治疗第6周肱二头肌、肱桡肌、小腿三头肌SWE值及UPDRS Ⅲ评分差异均无统计学意义(P均>0.05);完成治疗后AM组肱二头肌、肱桡肌SWE值及UPDRS Ⅲ评分均低于对照组(P均<0.05)。AM组治疗第6周及完成治疗后肱二头肌、肱桡肌、股直肌SWE值及UPDRS Ⅲ评分均较治疗前降低(P均<0.05),完成治疗后肱二头肌、股直肌SWE值及UPDRS Ⅲ评分均较治疗第6周降低(P均<0.05),但组内各时间点小腿三头肌SWE值差异无统计学意义(P>0.05)。对照组各时间点各肌肉SWE值差异均无统计学意义(P均>0.05)。治疗前、后肱二头肌SWE值差值及肌肉SWE值总和(肱二头肌、肱桡肌、股直肌及小腿三头肌)差值与UPDRS Ⅲ评分差值均呈正相关(r=0.57、0.55,P均<0.001)。结论 SWE能定量评估PD患者肌肉力学变化,可用于监测针灸治疗PD肌强直效果。 |
| 英文摘要: |
| Objective To observe the value of shear wave elastography (SWE) for evaluating effect of acupuncture and moxibustion for improving myotonic caused by Parkinson disease (PD). Methods Sixty PD patients were prospectively enrolled and randomly divided into the acupuncture and moxibustion group (AM group)and control group. Patients in AM group were treated with "treatment from yang" protocol, while those in control group underwent sham needle in acupuncture trials. SWE values of biceps brachii, brachioradialis, rectus femoris and triceps surae and unified PD rating scale (UPDRS) Ⅲ scores before, on the 6th week of treatment and after treatment were compared between and within groups, and the correlations were analyzed. Results Totally 52 cases were effective, including 28 cases in AM group and 24 cases in control group. Significant difference of SWE values of rectus femoris was found between groups before treatment (P<0.05), but not of SWE values and UPDRS-Ⅲ scores of biceps brachii, brachioradialis nor triceps surae before treatment and on the 6th week of treatment (all P>0.05). SWE values and UPDRS-Ⅲ scores of biceps brachii and brachioradialis were lower in AM group after treatment compared with those in control group (all P<0.05). In AM group, SWE values of biceps, radialis and rectus femoris, as well as UPDRS-Ⅲ scores decreased on the 6th week and after treatment compared with those before treatment (all P<0.05), SWE values and UPDRS-Ⅲ scores of biceps brachii and rectus femoris decreased after treatment compared with those on the 6th week of treatment (all P<0.05). No significant difference of SWE values of triceps calf was found among different time points in AM group (P>0.05), nor of SWE values of each muscle among different time points in control group (all P>0.05). The difference of biceps SWE values, of total muscle SWE values (biceps brachii, brachioradialis, rectus femoris and triceps surae) before and after treatment were positively correlated with the difference of UPDRS-Ⅲ scores (r=0.57, 0.55, both P<0.001). Conclusion SWE could quantitatively assess changes of muscle mechanics and monitor the effect of acupuncture and moxibustion for treating myotonia in PD patients. |
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