| 蒋庆红,刘百灵,张卉,唐毅.超声评估儿童克罗恩病活动度[J].中国医学影像技术,2023,39(7):1030~1033 |
| 超声评估儿童克罗恩病活动度 |
| Ultrasonic assessment of Crohn disease activity in children |
| 投稿时间：2023-02-21 修订日期：2023-04-22 |
| DOI：10.13929/j.issn.1003-3289.2023.07.017 |
| 中文关键词: Crohn病 儿童 超声检查 |
| 英文关键词:Crohn disease child ultrasonography |
| 基金项目: |
|
| 摘要点击次数: 855 |
| 全文下载次数: 536 |
| 中文摘要: |
| 目的 观察超声评估儿童克罗恩病(CD)活动度的价值。方法 回顾性分析24例经肠镜及活检病理确诊CD患儿,根据儿童CD活动指数(PCDAI)将其分为活动期(PCDAI ≥ 10.0,n=17)及缓解期(PCDAI<10.0,n=7),比较其超声所示病变肠壁厚度、肠壁分层、肠壁血供(Limberg分级)、肠系膜淋巴结肿大与否及肠外并发症的差异,分析肠壁厚度与C反应蛋白(CRP)及红细胞沉降率(ESR)的相关性。结果 活动期CD累及肠壁厚度、肠壁分层缺失占比及Limberg 分级均高于缓解期CD(P均<0.05),肠系膜淋巴结肿大占比则与缓解期CD差异无统计学意义(P>0.05)。超声于活动期CD患儿中检出3例肛周脓肿、2例腹腔积液及1例肛瘘;于缓解期CD患儿未见明确并发症。24例CD累及肠壁厚度均与CRP(rs=0.60,P=0.01)及ESR(rs=0.71,P<0.01)呈正相关。结论 超声可用于评估儿童CD活动度。 |
| 英文摘要: |
| Objective To observe the value of ultrasound in assessing activity of Crohn disease (CD) in children. Methods Data of 24 children with CD confirmed by colonoscopy and biopsy pathology were retrospectively analyzed. According to Pediatric CD activity index (PCDAI), the children were classified as active stage (PCDAI ≥ 10.0, n=17) or remission stage (PCDAI <10.0, n=7). Intestinal wall thickness, intestinal wall stratification, intestinal wall blood supply (Limberg grade), enlarged mesenteric lymph node or not and extraintestinal complications showed on ultrasonograms were compared between different stages of CD, and the correlations of intestinal wall thickness with C-reactive protein (CRP) and erythrocyte sedimentation rate (ESR) were analyzed. Results The intestinal wall thickness, proportion of missing intestinal wall stratification and Limberg grade of CD in active stage were higher than those in remission stage CD (all P<0.05), while the proportions of enlarged mesenteric lymph node were not significant different between different CD stage (P>0.05). Ultrasound detected 3 cases of perianal abscess, 2 cases of peritoneal effusion and 1 case of anal fistula in children with active CD, while no obvious complication was found in children of remission stage CD. The thickness of involved intestinal wall was positively correlated with CRP (rs=0.60, P=0.01) and ESR (rs=0.71, P<0.01) in all 24 cases. Conclusion Ultrasound could be used to assess CD activity in children. |
| 查看全文 查看/发表评论 下载PDF阅读器 |
|
|
|
