张煜堃,常佩佩,高冰冰,刘娜,罗贺丹,王楠,宋清伟,苗延巍.3.0T 3D高分辨率MR血管壁成像显示脑小血管病豆纹动脉改变[J].中国医学影像技术,2023,39(5):665~669
3.0T 3D高分辨率MR血管壁成像显示脑小血管病豆纹动脉改变
3.0T three-dimensional high resolution vessel wall MRI for displaying lenticulostriate artery changes of cerebral small vessel disease
投稿时间:2022-08-12  修订日期:2023-03-30
DOI:10.13929/j.issn.1003-3289.2023.05.005
中文关键词:  脑血管疾病  豆纹动脉  影像学总负荷评分  磁共振成像
英文关键词:cerebrovascular disorders  lenticulostriate artery  total imaging burden score  magnetic resonance imaging
基金项目:大连市科技创新基金计划(2020JJ27SN075)。
作者单位E-mail
张煜堃 大连医科大学附属第一医院放射科, 辽宁大连 116011  
常佩佩 大连医科大学附属第一医院放射科, 辽宁大连 116011  
高冰冰 大连医科大学附属第一医院放射科, 辽宁大连 116011  
刘娜 大连医科大学附属第一医院放射科, 辽宁大连 116011  
罗贺丹 大连医科大学附属第一医院放射科, 辽宁大连 116011  
王楠 大连医科大学附属第一医院放射科, 辽宁大连 116011  
宋清伟 大连医科大学附属第一医院放射科, 辽宁大连 116011  
苗延巍 大连医科大学附属第一医院放射科, 辽宁大连 116011 ywmiao716@163.com 
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中文摘要:
      目的 观察3.0T 3D高分辨率MR血管壁成像(3D HR-VMI)显示脑小血管病(CSVD)豆纹动脉(LSA)改变的价值,以及后者作为CSVD影像学标识的可行性。方法 纳入58例CSVD (CSVD组)及35例CSVD总负荷评分为0的其他疾病患者(对照组),评估3D HR-VMI重建图中LSA影像学特征,包括其数目、长度和曲折度;比较组间一般资料及影像学表现的差异,以logistic回归分析评估CSVD发生及CSVD总负荷评分的独立危险因素。结果 组间高血压发生率及LSA数目差异均有统计学意义(P均<0.05)。CSVD患者CSVD总负荷评分与LSA数目呈负相关(r=-0.48,P<0.001)。高血压和LSA数目减少是CSVD发生的独立危险因素;高龄、饮酒及LSA数目减少为CSVD总负荷评分增高的独立危险因素。结论 3.0T 3D HR-VMI可清晰显示CSVD LSA改变;LSA数目减少为发生CSVD及CSVD总负荷评分增高的独立危险因素,可作为CSVD的影像学标识。
英文摘要:
      Objective To observe the value of 3.0T three-dimensional high resolution vessel wall MRI (3D HR-VMI) for displaying lenticulostriate artery (LSA) changes of cerebral small vessel disease (CSVD), and the feasibility of taken LSA changes as imaging markers of CSVD. Methods Fifty-eight CSVD patients (CSVD group) and 35 cases of other diseases with CSVD total burden scores of 0 (control group) were enrolled. The imaging characteristics, including the number, length and tortuosity of LSA were observed on 3D HR-VMI reconstruction images. The general information and imaging characteristics were compared between 2 groups, and logistic regression analysis was performed, the independent risk factors for the occurrence of CSVD and CSVD total burden scores were evaluated. Results There were significant differences in the incidence of hypertension and the numbers of LSA between groups (both P<0.05). CSVD total burden scores was negatively correlated with the number of LSA in CSVD patients (r=-0.48, P<0.001). Hypertension and decreased number of LSA were independent risk factors of the occurrence of CSVD, while aging, alcohol consumption and decreased number of LSA were independent risk factors for increase of CSVD total burden scores. Conclusion 3.0T 3D HR-VMI could clearly display LSA changes of CSVD. Decreased number of LSA was an independent risk factor for the occurrence of CSVD and increased CSVD total burden scores, which could be taken as imaging marker of CSVD.
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