| 陈志强,宋娜,张少茹,张丹,王卓,蔡磊,马爱玲.不同T、M分期前列腺癌小视野体素内不相干运动弥散加权成像参数特征[J].中国医学影像技术,2022,38(12):1853~1856 |
| 不同T、M分期前列腺癌小视野体素内不相干运动弥散加权成像参数特征 |
| Characteristics of reduced field-of-view intravoxel incoherent motion diffusion weighted imaging parameters of different T and M stage prostate cancers |
| 投稿时间：2022-05-12 修订日期：2022-10-24 |
| DOI：10.13929/j.issn.1003-3289.2022.12.019 |
| 中文关键词: 前列腺肿瘤 肿瘤分期 体素内不相干运动 弥散磁共振成像 |
| 英文关键词:prostatic neoplasms neoplasm staging intravoxel incoherent motion diffusion magnetic resonance imaging |
| 基金项目:宁夏回族自治区自然科学基金项目（2022AAC03472）。 |
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| 中文摘要: |
| 目的 观察不同T、M分期前列腺癌小视野体素内不相干运动（IVIM）弥散加权成像（DWI）参数特征。方法 回顾性分析46例接受前列腺MR常规序列成像和小视野IVIM-DWI的不同临床T、M分期及Gleason评分前列腺癌患者，观察其间标准表观弥散系数（ADCstandard）、扩散系数（D）、伪扩散系数（D*）及快速扩散分数（f）差异，分析临床T、M分期及Gleason评分与上述参数的相关性。结果 不同T分期前列腺癌ADCstandard、D及f差异具有统计学意义（P均<0.05）；其中，ADCstandard和f在T2与T3期、T2与T4期之间差异均有统计学意义（P均<0.05），D在T2与T4期、T3与T4期之间差异均有统计学意义（P均<0.05）。不同M分期及不同Gleason评分前列腺癌ADCstandard和D差异均有统计学意义（P均<0.05）。前列腺癌T分期与ADCstandard、D及f呈负相关（r=－0.69、－0.75、－0.53，P均<0.05），M分期和Gleason评分均与ADCstandard（r=－0.34、－0.50，P均<0.05）及D （r=－0.43、－0.53，P均<0.05）呈负相关。结论 不同T分期前列腺癌ADCstandard、D及f存在差异，且T分期与三者均呈负相关；不同M分期前列腺癌ADCstandard和D存在差异，且M分期与二者均呈负相关。 |
| 英文摘要: |
| Objective To observe the characteristics of reduced field-of-view intravoxel incoherent motion (IVIM) diffusion weighted imaging (DWI) parameters ofwith different T and M stage prostate cancers. Methods Data of 46 patients with prostate cancer who underwent routine MR imaging and reduced field-of-view IVIM-DWI were retrospectively analyzed. The standard apparent diffusion coefficient (ADCstandard), diffusion coefficient (D), pseudo diffusion coefficient (D*) and rapid diffusion score (f) were compared among prostate cancers with different clinical T and M stages and Gleason scores, and the correlation of T stage, M stage, Gleason score and the above parameters were explored. Results There were significant differences of ADCstandard, D and f among prostate cancers with different T stages (all P<0.05). ADCstandard and f were significant different between T2 and T3, T2 and T4 stage, also of D between T2 and T4, T3 and T4 stage prostate cancers (all P<0.05). There were significant differences of ADCstandard and D among prostate cancers with different M stages and Gleason scores (all P<0.05). T stage of prostate cancer was negatively correlated with ADCstandard, D and f (r=-0.69, -0.75, -0.53, all P<0.05), while M stage and Gleason score were both negatively correlated with ADCstandard(r=-0.34, -0.50, both P<0.05) and D (r=-0.43, -0.53, both P<0.05). Conclusion Significant differences of ADCstandard, D and f existed among prostate cancers with different T stages, which were all negatively correlated with T stage. There were significant differenced of ADCstandard and D between prostate cancers with different M stages, which were negatively correlated with M stages. |
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