| 李莉明,黄文鹏,赵慧萍,王睿,梁盼,高剑波.胃肝样腺癌CT及临床表现[J].中国医学影像技术,2022,38(5):713~716 |
| 胃肝样腺癌CT及临床表现 |
| CT and clinical manifestations of hepatoid adenocarcinoma of stomach |
| 投稿时间：2021-06-27 修订日期：2021-12-17 |
| DOI：10.13929/j.issn.1003-3289.2022.05.018 |
| 中文关键词: 胃肿瘤 腺癌 体层摄影术,X线计算机 |
| 英文关键词:stomach neoplasms adenocarcinoma tomography, X-ray computed |
| 基金项目:国家自然科学基金(81971615)。 |
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| 中文摘要: |
| 目的 观察胃肝样腺癌(HAS)CT及临床表现。方法 收集30例经术后病理确诊的HAS患者(HAS组)及30例术后病理确诊为非HAS的胃腺癌(GA)患者(非HAS组);对比观察2组CT及临床表现。结果 2组患者性别、年龄、病程及主要症状差异均无统计学意义(P均＞0.05)。肿瘤标志物检查显示,HAS组17例(56.67%,17/30)血清甲胎蛋白(AFP)升高。HAS组病灶最大径大于、而CT值静脉期-动脉期小于非HAS组(P均＜0.05),且组间强化程度及强化方式差异均有统计学意义(P均＜0.05)。HAS组转移淋巴结短径及术后转移率均高于非HAS组(P均＜0.05),而肿瘤分化程度、患者中位无进展生存期及中位总生存期均低于非HAS组(P均＜0.05)。结论 HAS临床表现不典型,患者多伴血清AFP升高,预后较差;其CT表现具有一定特征性,可据以与非HAS GA相鉴别。 |
| 英文摘要: |
| Objective To observe CT and clinical manifestations of hepatoid adenocarcinoma of stomach (HAS).Methods Totally 30 patients with HAS (HAS group) and 30 with non-HAS gastric adenocarcinoma (GA, non-HAS group) confirmed by postoperative pathology were enrolled. CT and clinical manifestations were observed and compared between groups.Results Tumor marker examination showed 17 cases (56.67%, 17/30) in HAS group with increased serum alpha fetal protein (AFP) level. There was no significant difference of patients' gender, age, course of disease and main symptoms between groups (all P＞0.05). The maximum diameter of lesions in HAS group was larger than that in non-HAS group, while the difference of CT value of lesions between venous phase and arterial phase in HAS group was smaller than that in non-HAS group (both P＜0.05), and the enhancement degrees and modes were significantly different between groups (both P＜0.05). The short diameter of metastatic lymph nodes and postoperative metastasis rate in HAS group were higher than those in non-HAS group (both P＜0.05), while the tumor differentiation degree, the patients' median progression free survival and median overall survival in HAS group all lower than those in non-HAS group (all P＜0.05).Conclusion HAS had atypical clinical manifestations, with elevated serum AFP and poor prognosis. CT manifestations of HAS were of certain characteristics, which could be used to distinguish HAS from non-HAS GA. |
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