| 尚康康,闫志华,杜晓光,周会,程兵.xSPECT Quant联合唾液腺显像评估分化型甲状腺癌甲状腺全切术后131I治疗前患者腮腺和残留甲状腺功能[J].中国医学影像技术,2022,38(5):663~668 |
| xSPECT Quant联合唾液腺显像评估分化型甲状腺癌甲状腺全切术后131I治疗前患者腮腺和残留甲状腺功能 |
| xSPECT Quant combined with salivary gland scintigraphy for evaluating parotid gland function and residual thyroid gland in differentiated thyroid carcinoma patients after total thyroidectomy and before 131I treatment |
| 投稿时间：2021-03-23 修订日期：2022-02-28 |
| DOI：10.13929/j.issn.1003-3289.2022.05.005 |
| 中文关键词: 甲状腺肿瘤 碘同位素 放射性核素显像 体层摄影术,发射型计算机,单光子 体层摄影术,X线计算机 |
| 英文关键词:thyroid neoplasms iodine isotopes radionuclide imaging tomography, emission-computed, single-photon tomography, X-ray computed |
| 基金项目: |
|
| 摘要点击次数: 2052 |
| 全文下载次数: 492 |
| 中文摘要: |
| 目的 观察xSPECT Quant联合唾液腺显像(SGS)评估分化型甲状腺癌(DTC)甲状腺全切术后131I治疗前患者腮腺和残留甲状腺功能的价值。方法 前瞻性纳入60例拟接受131I治疗的甲状腺全切术后DTC患者,于131I治疗前日行头颈部xSPECT Quant断层融合显像及SGS,计算左、右侧及整体腮腺摄取指数(UI)、最大排泌率(MSR)、最大标准摄取值(SUVmax)、平均标准摄取值(SUVmean)及残留甲状腺SUVmax、SUVmean;根据xSPECT Quant断层图像中颈部存在残留甲状腺组织与否将患者分为残留组(n=32)和无残留组(n=28),依照参数分析法评估腮腺功能结果而分为功能正常组(n=43)和功能受损组(n=17);观察xSPECT Quant联合SGS评估腮腺和残留甲状腺功能的价值。结果 功能正常组与功能受损组左、右侧腮腺UI及SUVmean差异均有统计学意义(P均＜0.05),腮腺整体UI与SUVmax,MSR与SUVmax、SUVmean均呈低度相关(r=0.356、0.327、0.380,P均＜0.01),而UI与SUVmean呈中度相关(r=0.531,P＜0.01)。残留组与无残留组24 h摄碘率差异有统计学意义(P＜0.05),且残留甲状腺SUVmax与24 h摄碘率呈低度相关(r=0.381,P＜0.05)。结论 xSPECT Quant联合SGS对评估DTC甲状腺全切术后131I治疗前患者腮腺和残留甲状腺功能具有一定价值,可初步筛查腮腺功能障碍并评估残留甲状腺的摄碘能力。 |
| 英文摘要: |
| Objective To observe the value of xSPECT Quant combined with salivary gland scintigraphy (SGS) for evaluating parotid gland function and residual thyroid gland in patients with differentiated thyroid carcinoma (DTC) after total thyroidectomy and before 131I treatment.Methods Totally 60 DTC patients after total thyroidectomy who would underwent 131I treatment were prospectively enrolled. Head and neck xSPECT Quant tomographic fusion imaging and SGS were performed the day before 131I treatment. The uptake index (UI), maximum excretion rate (MSR), maximum standard uptake value (SUVmax), mean standard uptake value (SUVmean) of left, right and whole parotid glands, as well as SUVmax and SUVmean of the residual thyroid were calculated. The patients were divided into residual group (n=32) and non-residual group (n=28) according to whether with or without residual thyroid tissue on xSPECT Quant tomographic images, also into normal function group (n=43) and impaired function group (n=17) according to results of parametric analysis for parotid gland function. The value of xSPECT Quant combined with SGS for evaluating parotid gland function and residual thyroid gland was evaluated.Results Significant differences of UI and SUVmean of left and right parotid gland were found between normal function group and impaired function group (all P＜0.05). There were low correlations between UI and SUVmax of whole parotid gland, as well as between MSR and SUVmax, SUVmean (r=0.356, 0.327, 0.380, all P＜0.01), while UI was moderately correlated with SUVmean (r=0.531, P＜0.01). Significant difference of 24 h iodine uptake rate was detected between residual group and non-residual group (P＜0.05), while SUVmax of residual thyroid gland was lowly correlated with 24 h iodine uptake rate (r=0.381, P＜0.05).Conclusion xSPECT Quant combined with SGS had certain value for evaluating parotid gland the function and residual thyroid gland in DTC patients after total thyroidectomy before 131I treatment, which could not only initially screen parotid gland dysfunction, but also evaluate iodine uptake ability of residual thyroid. |
| 查看全文 查看/发表评论 下载PDF阅读器 |
|
|
|
