| 林帅,鹿松,张静,房娜,靳飞,李超伟,姜雯雯,曾磊,刘翠玉,王艳丽.18F-FDG PET/CT诊断肺孤立性肉芽肿性炎[J].中国医学影像技术,2022,38(4):536~539 |
| 18F-FDG PET/CT诊断肺孤立性肉芽肿性炎 |
| 18F-FDG PET/CT for diagnosis of solitary granulomatous inflammation in lung |
| 投稿时间：2021-07-26 修订日期：2021-11-12 |
| DOI：10.13929/j.issn.1003-3289.2022.04.014 |
| 中文关键词: 肺 肉芽肿性炎 体层摄影术,X线计算机 正电子发射断层显像 |
| 英文关键词:lung granulomatous inflammation tomography, X-ray computed positron-emission tomography |
| 基金项目: |
| 作者 | 单位 | E-mail | | 林帅 | 青岛大学附属青岛市中心医院PET/CT中心, 山东 青岛 266042 | | | 鹿松 | 青岛市妇女儿童医院医学影像科, 山东 青岛 266034 | | | 张静 | 青岛大学附属青岛市中心医院PET/CT中心, 山东 青岛 266042 | | | 房娜 | 青岛大学附属青岛市中心医院PET/CT中心, 山东 青岛 266042 | | | 靳飞 | 青岛大学附属青岛市中心医院PET/CT中心, 山东 青岛 266042 | | | 李超伟 | 青岛大学附属青岛市中心医院PET/CT中心, 山东 青岛 266042 | | | 姜雯雯 | 青岛大学附属青岛市中心医院PET/CT中心, 山东 青岛 266042 | wangyanli1105@163.com | | 曾磊 | 青岛大学附属青岛市中心医院PET/CT中心, 山东 青岛 266042 | | | 刘翠玉 | 青岛大学附属青岛市中心医院PET/CT中心, 山东 青岛 266042 | | | 王艳丽 | 青岛大学附属青岛市中心医院PET/CT中心, 山东 青岛 266042 | |
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| 中文摘要: |
| 目的 观察18F-FDG PET/CT诊断肺孤立性肉芽肿性炎的价值。方法 观察60例经病理学证实肺孤立性肉芽肿性炎患者的18F-FDG PET/CT早期和延迟显像，分析病灶CT征象并测量18F-FDG代谢参数，分别评价PET、CT及PET/CT诊断肺肉芽肿性炎的准确率。采用Spearman相关性分析评价早期最大标准摄取值（SUVmax）与病灶最大径的相关性。结果 60例中，22例（22/60，36.67%）病灶位于左肺，38例（38/60，63.33%）位于右肺；病灶最大径0.4~8.4 cm；14例（14/60，23.33%）病灶为圆形或类圆形，46例（46/60，76.67%）形态不规则；CT值为22.0~77.0 HU；43例（43/60，71.67%）病灶密度均匀；41例（41/60，68.33%）病灶可见"反3字"征或尖角征，6例（6/60，10.00%）出现刀切征，1例（1/60，1.67%）出现晕征；4例（4/60，6.67%）病灶内部出现空洞；6例（6/60，10.00%）见支气管充气征；26例（26/60，43.33%）病灶位于胸膜下，其中20例（20/26，76.92%）病灶与胸膜呈宽基底相连，包括3例（3/20，15.00%）见胸膜凹陷征。60例病灶的早期中位SUVmax为3.95（1.73，6.78），低于延迟期的4.55（2.52，7.65）（P<0.05）；中位RI为12.22%（5.89%，24.70%）。病灶早期SUVmax与其最大径呈正相关（r=0.57，P<0.05）。18F-FDG PET/CT诊断肺肉芽肿性炎的准确率为91.67%（55/60），高于单独PET（61.67%，37/60）或CT（78.33%，47/60）检查（P均<0.05）；CT准确率高于PET（P<0.05）。结论 肺孤立性肉芽肿性炎18F-FDG PET/CT表现具有一定特征性；18F-FDG PET/CT诊断准确率高于单一PET及CT。 |
| 英文摘要: |
| Objective To observe the value of 18F-FDG PET/CT imaging for diagnosis of solitary granulomatous inflammation in lung. Methods Early and delayed 18F-FDG PET/CT imaging of 60 patients with pulmonary solitary granulomatosis confirmed by pathology were observed. CT manifestations of the lesions were analyzed, the metabolic parameters of 18F-FDG were measured, and the diagnostic accuracy of PET/CT, CT and PET for pulmonary solitary granulomatosis were evaluated, respectively. Spearman correlation analysis was used to explore the correlation between early maximum standard uptake value (SUVmax) and maximum diameter of the lesions. Results Among 60 cases of pulmonary solitary granulomatosis, the lesions, located in the left lung in 22 cases (22/60, 36.67%), while in the right lung in 38 cases (38/60, 63.33%). The maximum diameter of the lesions was 0.4-8.4 cm. Round or quasi-round lesions were found in 14 cases (14/60, 23.33%), while irregular shaped lesions were observed in 46 cases (46/60, 76.67%), with CT value of 22.0-77.0 HU. Homogeneous density lesion was detected in 43 cases (43/60, 71.67%), "inverted 3 sign" or sharp angle sign was observed in 41 cases (41/60, 68.33%), while knife cut sign and halo sign were noticed in 6 (6/60, 10.00%) and 1 case (1/60, 1.67%), and cavities inside the lesions and bronchial inflation were found in 4 (4/60, 6.67%) and 6 cases (6/60, 10.00%), respectively. Subpleural lesions were observed in 26 cases (26/60, 43.33%). Lesions connected with the pleura in a wide base in 20 cases (20/26, 76.92%), with pleural indentation in 3 cases (3/20, 15.00%). The median of the early SUVmax of 60 lesions was 3.95 (1.73, 6.78), lower than that of the delayed stage (4.55, P<0.05). The median RI of lesions was 12.22% (5.89%, 24.70%). There was a positive correlation between early SUVmax and the maximum diameter (r=0.57, P<0.05). The accuracy of 18F-FDG PET/CT in diagnosing pulmonary granulomatous inflammation was 91.67% (55/60), higher than that of PET (61.67%, 37/60) or CT (78.33%, 47/60) (both P<0.05), and of CT was higher than that of PET (P<0.05). Conclusion 18F-FDG PET/CT manifestations of solitary granulomatous inflammation in lung had certain characteristics. The diagnostic accuracy of PET/CT was higher than that of single PET or CT. |
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