刘婷婷,孙珂,张晶晶,刘保平,韩星敏.18F-FDG PET/CT观察原发性睾丸弥漫大B细胞淋巴瘤[J].中国医学影像技术,2022,38(3):427~430
18F-FDG PET/CT观察原发性睾丸弥漫大B细胞淋巴瘤
18F-FDG PET/CT for observation of primary testicular diffuse large B cell lymphoma
投稿时间:2021-06-04  修订日期:2021-11-06
DOI:10.13929/j.issn.1003-3289.2022.03.024
中文关键词:  睾丸肿瘤  淋巴瘤,B细胞  正电子发射断层显像  体层摄像术,X线计算机  18氟脱氧葡萄糖
英文关键词:testicular neoplasms  lymphoma, B-cell  positron-emission tomography  tomography, X-ray computed  fluorodeoxyglucose F18
基金项目:
作者单位E-mail
刘婷婷 郑州大学第一附属医院核医学科, 河南 郑州 450052  
孙珂 郑州大学第一附属医院核医学科, 河南 郑州 450052  
张晶晶 郑州大学第一附属医院核医学科, 河南 郑州 450052  
刘保平 郑州大学第一附属医院核医学科, 河南 郑州 450052  
韩星敏 郑州大学第一附属医院核医学科, 河南 郑州 450052 xmhan@zzu.edu.cn 
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中文摘要:
      目的 观察原发性睾丸弥漫大B细胞淋巴瘤(PT-DLBCL)的18F-FDG PET/CT表现及其诊断价值。方法 回顾性分析5例经病理确诊的PT-DLBCL患者的术前及化学治疗前18F-FDG PET/CT资料,观察其原发灶、淋巴结及结外病灶表现,并分析18F-FDG PET/CT的诊断价值。结果 5例PT-DLBCL中,18F-FDG PET/CT示3例双侧睾丸病变、2例右侧睾丸病变;其原发灶最大标准摄取值(SUVmax)为13.90~26.80,中位SUVmax为16.00。5例中,4例伴淋巴结内病变,见于腹膜后4例、盆腔3例、腹股沟及颈部各1例,其SUVmax 4.40~24.70,中位SUVmax为14.40;3例伴睾丸外结外病变,累及右侧臀部皮下组织、右上腹部皮肤及口咽各1例,病灶SUVmax分别为4.30、5.20及40.90。5例患者均接受全身化学治疗,1例完全缓解(CR),3例部分缓解(PR),1例疾病进展(PD)。结论 18F-FDG PET/CT可见PT-DLBCL病灶摄取增高,对于诊断其睾丸原发灶、淋巴结病变及结外病变均具一定价值。
英文摘要:
      Objective To observe the value of 18F-FDG PET/CT for diagnosis of primary testicular diffuse large B cell lymphoma (PT-DLBCL). Methods 18F-FDG PET/CT data of 5 patients with PT-DLBCL before surgical operation and chemotherapy were retrospectively analyzed. The manifestations of primary lesions of PT-DLBCL, as well as lymph nodes and extranodal lesions of PT-DLBCL were observed, and the diagnostic value of 18F-FDG PET/CT was analyzed. Results Among 5 cases of PT-DLBCL, 18F-FDG PET/CT showed bilateral testicular lesions in 3 cases and only right side testicular lesions in 2 cases. The maximum standard uptake values (SUVmax) of primary testicular lesions were 13.90-26.80, and the median SUVmax was 16.00. Lymph node lesions were found in 4 cases, including retroperitoneum lesions in all 4 cases, pelvic lesions in 3 cases, and groin and neck lesions in 1 case, respectively, with SUVmax of 4.40-24.70 and the median SUVmax of 14.40. Extranodal lesions were observed in 3 cases, which involved the subcutaneous tissue of right hip, the skin of right upper abdomen and the oropharynx, respectively, and the SUVmax was 4.30, 5.20 and 40.90, respectively. All 5 patients underwent systemic chemotherapy, then complete remission (CR) was observed in 1 case, while partial remission (PR) in 3 cases of and progression disease (PD) in 1 case. Conclusion 18F-FDG PET/CT could show increased uptake of lesions of PT-DLBCL, which was of certain value for diagnosis of primary testicular lesions, lymph node lesions and extranodal lesions.
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