杨秀荣,李英丽,柴晓明.原发性干燥综合征继发肺淀粉样变性影像学表现以及文献复习[J].中国医学影像技术,2022,38(3):384~387
原发性干燥综合征继发肺淀粉样变性影像学表现以及文献复习
Imaging manifestations of pulmonary amyloidosis secondary to primary Sj gren syndrome and literature review
投稿时间:2021-07-10  修订日期:2021-10-20
DOI:10.13929/j.issn.1003-3289.2022.03.015
中文关键词:  干燥综合征  淀粉样变    诊断显像
英文关键词:Sjögren's syndrome  amyloidosis  lung  diagnostic imaging
基金项目:
作者单位E-mail
杨秀荣 厦门大学附属第一医院杏林分院放射科, 福建 厦门 361022  
李英丽 厦门大学附属第一医院放射科, 福建 厦门 361003  
柴晓明 厦门大学附属第一医院放射科, 福建 厦门 361003 chxmfshk@163.com 
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中文摘要:
      目的 结合回顾文献分析原发性干燥综合征(pSS)继发肺淀粉样变性(PA)的CT及18F-FDG PET/CT表现。方法 回顾性收集4例经病理证实的pSS继发PA患者,均接受胸部CT检查,其中1例接受全身18F-FDG PET/CT检查;结合文献分析pSS继发PA的CT及18F-FDG PET/CT表现。结果 4例胸部CT均表现为双肺多发结节或团块,病灶最大径3~36 mm、中位最大径13 mm,CT值15~410 HU、中位CT值65 HU,部分伴钙化(3/4);并均见肺囊腔样病变(4/4)。18F-FDG PET/CT示部分结节18F-FDG摄取轻度升高。结论 pSS继发PA的CT表现具有一定特征性;结合18F-FDG PET/CT有助于与肿瘤性病变相鉴别。
英文摘要:
      Objective To analyze imaging manifestations of pulmonary amyloidosis (PA) secondary to primary Sj gren syndrome (pSS) combined with literature review. Methods Four patients with PA secondary to pSS confirmed by pathology were retrospectively collected. All patients underwent chest CT examination, and 1 patient underwent whole body 18F-FDG PET/CT. The imaging manifestations of PA secondary to pSS were analyzed combined with literature review. Results Chest CT showed multiple lung nodules or masses in both sides (4/4), with the maximum diameter of 3-36 mm and the median maximum diameter of 13 mm. The CT value of lesions was 15-410 HU, with the median CT value of 65 HU. Some lesions were found accompanied by calcifications (3/4), while cystic lesions (4/4) were found in all 4 cases. 18F-FDG PET/CT showed slightly increased 18F-FDG uptake in some nodules. Conclusion CT manifestations of PA secondary to pSS had certain characteristics, which combined with 18F-FDG PET/CT examination were helpful to distinguishing PA from tumor lesions.
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