| 程祖胜,夏国园,王爱芝,曹世林,王亮,诸绍锋,戚洪阳,裘孝敏,陈琳霞.长期住院精神分裂症患者结肠形态变化[J].中国医学影像技术,2022,38(2):243~247 |
| 长期住院精神分裂症患者结肠形态变化 |
| Colonic morphological changes of long-term hospitalized schizophrenic patients |
| 投稿时间：2020-08-03 修订日期：2021-12-21 |
| DOI：10.13929/j.issn.1003-3289.2022.02.019 |
| 中文关键词: 精神分裂症 结肠 解剖学 X线 |
| 英文关键词:schizophrenia colon anatomy X-rays |
| 基金项目:浙江省医药卫生科技计划（2019KY722）、绍兴市卫生计生科技计划（2017QN010）。 |
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| 中文摘要: |
| 目的 观察长期住院的精神分裂症（Sc）患者结肠形态变化，并分析其原因。方法 回顾性分析以数字X线摄影（DR）获得的780例长期住院Sc患者（Sc组）及663名健康志愿者（对照组）的腹部站立前后位（APPA）片，观察结肠形态变化，并以Spearman相关法分析形态变化与临床资料的相关性，探讨其原因。结果 Sc组与对照组受检者性别及年龄差异均无统计学意义（F=0.41、2.16，P=0.53、0.19）。Sc组780例中，209例（209/780，26.79%）存在结肠形态变化；对照组663名中，59名（59/663，8.90%）存在结肠形态变化。Sc组结肠形态变化发生率明显高于对照组（χ2=75.98，P<0.001）。Sc组结肠形态变化与患者年龄（r=0.964，P<0.001）、病程（r=0.958，P<0.001）及抗精神病药物（AD）治疗时间（r=0.976，P<0.001）呈高度正相关。结论 长期住院Sc患者存在结肠形态变化且类型多样，与年龄、病程及AD治疗时间有关。 |
| 英文摘要: |
| Objective To observe the colonic morphological changes and causes of long-term hospitalized schizophrenic (Sc) patients. Methods Digital radiography (DR) anterior-posterior position abdomen (APPA) images of 780 long-term hospitalized Sc patients (Sc group) and 663 healthy volunteers (control group) were retrospectively analyzed. The changes of colonic morphology were observed, and the correlations of colonic morphology and clinical data were analyzed with Spearman correlation analysis to explore the causes of these changes. Results There was no significant difference of gender nor age between groups (F=0.41, 2.16; P=0.53, 0.19). Among 780 patients in SC group, colonic morphological changes were observed in 209 cases (209/780, 26.79%), while among 663 subjects in control group, colonic morphological changes were found in 59 subjects (59/663, 8.90%). The incidence of colonic morphological changes of Sc group was significantly higher than that of control group (χ2=75.98, P<0.001). The morphological changes of colon in Sc patients were highly positively correlated with age (r=0.964, P<0.001), course of disease (r=0.958, P<0.001) and treatment time of antipsychotic drug (AD) (r=0.976, P<0.001). Conclusion Various colonic morphological changes occurred in long-term hospitalized Sc patients, being related to patients' age, course of disease and treatment time of AD. |
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