| 尹晨旺,鲁琳,史宇静,张振,高艺源.MR特征追踪技术评价急性心肌炎患者左心房功能[J].中国医学影像技术,2022,38(2):195~199 |
| MR特征追踪技术评价急性心肌炎患者左心房功能 |
| Cardiac MR feature tracking for evaluating left atrial function of acute myocarditis patients |
| 投稿时间：2021-01-27 修订日期：2021-09-05 |
| DOI：10.13929/j.issn.1003-3289.2022.02.009 |
| 中文关键词: 心肌炎 心房功能,左 磁共振成像 |
| 英文关键词:myocarditis atrial function, left magnetic resonance imaging |
| 基金项目:深圳市龙岗区经济与科技发展专项资金医疗卫生科技计划项目（LGKCYLWS2020004）。 |
|
| 摘要点击次数: 955 |
| 全文下载次数: 590 |
| 中文摘要: |
| 目的 采用心脏MR特征追踪（CMR-FT）技术定量评估急性心肌炎患者左心房功能改变，分析心房应变参数诊断急性心肌炎的价值。方法 对28例临床诊断急性心肌炎患者（病例组）及26名健康志愿者（对照组）采集CMR电影序列图像，经后处理分析得到左心室功能、左心房容积及应变参数。采用受试者工作特征（ROC）曲线，计算曲线下面积（AUC），评价差异有统计学意义的左心房容积及应变参数诊断急性心肌炎的效能。结果 病例组左心室收缩末期容积指数（LVESVI）大于对照组（P=0.046），其余左心功能参数组间差异均无统计学意义（P均>0.05）。相比对照组，病例组左心房总排空分数（EFtotal）、被动排空分数（EFpassive）、总应变（εs）、被动应变（εe）及早期负向应变率峰值（SRe）均显著降低（P均<0.05）。ROC曲线显示，左心房应变参数εs、εe及SRe诊断急性心肌炎的AUC分别为0.77、0.81及0.75。结论 急性心肌炎患者即使左心室收缩功能正常，左心房亦已存在储存和管道功能受损；CMR-FT技术定量评估左心房应变功能有助于早期诊断急性心肌炎。 |
| 英文摘要: |
| Objective To quantitatively evaluate the changes of left atrial function in acute myocarditis with cardiac MR feature tracking (CMR-FT) technology, and to analyze the value of atrial strain parameters for diagnosis of acute myocarditis. Methods CMR cine imaging were collected from 28 patients with clinically diagnosed acute myocarditis (patient group) and 26 healthy volunteers (control group). The left ventricular function, left atrial volume and strain parameters were obtained with post-processing analysis. Receiver operating characteristic (ROC) curves of parameters being statistically different between groups were drawn, and the corresponding area under the curve (AUC) were calculated to evaluate the diagnostic value of strain parameters of acute myocarditis. Results The left ventricular end-systolic volume index (LVESVI) in patient group was higher than that in control group (P=0.046), while no statistical difference of the other left heart function parameters was found between groups (all P>0.05). Compared with control group, the total left atrial emptying fraction (EFtotal), passive emptying fraction (EFpassive), total strain (εs), passive strain (εe) and peak early negative strain rate (SRe) in patient group significantly reduced (all P<0.05). ROC curve showed that the AUC of εs, εe, and SRe for diagnosis of acute myocarditis was 0.77, 0.81 and 0.75, respectively. Conclusion Even with normal left ventricular systolic function, acute myocarditis patients had impaired left atrium storage and conduit function.Quantitative assessment of left atrial strain function based on CMR-FT technology was useful for early diagnosis of acute myocarditis. |
| 查看全文 查看/发表评论 下载PDF阅读器 |
|
|
|
