| 付雪林,黄国中,邓军.奥沙利铂相关肝窦阻塞综合征CT及MRI研究进展[J].中国医学影像技术,2021,37(11):1735~1739 |
| 奥沙利铂相关肝窦阻塞综合征CT及MRI研究进展 |
| CT and MRI research progresses of oxaliplatin-associated hepatic sinusoidal obstruction syndrome |
| 投稿时间：2020-08-26 修订日期：2021-07-25 |
| DOI：10.13929/j.issn.1003-3289.2021.11.033 |
| 中文关键词: 化学和药物性肝损伤 诊断显像 肝静脉阻塞症 奥沙利铂 |
| 英文关键词:chemical and drug induced liver injury diagnostic imaging hepatic veno-occlusive disease oxaliplatin |
| 基金项目:江西省卫生健康委科技计划（202130388）。 |
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| 中文摘要: |
| 奥沙利铂（OXA）相关肝窦阻塞综合征（HSOS）是一类以肝窦内皮损伤为主的药物性肝损伤，早期症状隐匿，实验室检查肝功能正常或轻度异常，临床确诊困难。监测OXA诱导HSOS的发生发展对预防和治疗相关并发症具有重要意义。CT、MRI可用于无创评估药物性肝损伤。本文就CT、MRI评估OXA诱导HSOS的进展进行综述。 |
| 英文摘要: |
| Oxaliplatin (OXA)-associated hepatic sinusoidal obstruction syndrome (HSOS) is a kind of drug-induced liver injuries mainly caused by hepatic sinusoidal endothelial injury. The early clinical symptoms of HSOS are often unclear, with normal or mild abnormal liver function, therefore difficult to diagnose. Monitoring the occurrence and development of OXA induced HSOS is of great significances for prevention and treatment of related complications. CT and MRI can be used to non-invasively evaluate drug-induced liver injury. The research progresses of CT and MRI for evaluation on OXA induced HSOS were reviewed in this article. |
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