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吴彪,弓健,程勇,唐勇进,凌雪英,徐浩.对比¹⁸F-FDG PET/CT与PET/MRI诊断胰腺占位性病变[J].中国医学影像技术,2021,37(11):1614~1618

对比¹⁸F-FDG PET/CT与PET/MRI诊断胰腺占位性病变

Comparison on ¹⁸F-FDG PET/CT and PET/MRI for diagnosing space-occupying pancreatic lesions

投稿时间：2021-04-08 修订日期：2021-09-13

DOI：10.13929/j.issn.1003-3289.2021.11.005

中文关键词: 胰腺肿瘤胰腺炎磁共振成像正电子发射断层显像 18F氟脱氧葡萄糖

英文关键词:pancreatic neoplasms pancreatitis magnetic resonance imaging positron-emission tomography fluorodeoxyglucose F18

基金项目:

作者	单位	E-mail
吴彪	暨南大学附属第一医院核医学科, 广东广州 510630
弓健	暨南大学附属第一医院核医学科, 广东广州 510630
程勇	暨南大学附属第一医院核医学科, 广东广州 510630
唐勇进	暨南大学附属第一医院核医学科, 广东广州 510630
凌雪英	暨南大学附属第一医院核医学科, 广东广州 510630
徐浩	暨南大学附属第一医院核医学科, 广东广州 510630	txh@jnu.edu.cn

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中文摘要:

目的比较¹⁸F-FDG PET/CT与PET/MRI诊断胰腺占位性病变的价值。方法回顾性分析34例接受体部¹⁸F-FDG PET/CT检查及上腹部MR扫描的胰腺占位患者，对比观察¹⁸F-FDG PET/CT与PET/MRI判断良恶性病灶、图像融合匹配度、图像质量及图像附加信息，评估二者诊断胰腺占位性病变的价值。结果 34例共检出37个胰腺病灶。PET/CT诊断7个良性病灶、30个恶性病灶，其诊断胰腺癌的敏感度、特异度和准确率分别为95.83%、46.15%和78.38%；PET/MRI诊断11个良性病灶、26个恶性病灶，其诊断胰腺癌的敏感度、特异度和准确率分别为100%、84.61%和94.59%，诊断准确率显著高于PET/CT（χ²=4.16，P=0.04）。PET/CT与PET/MR图像融合匹配度差异无统计学意义（P>0.05）。CT、MR、PET/CT及PET/MR图像质量差异无统计学意义（P>0.05）。27.03%（10/37）的图像附加信息评分为-1分，8.11%（3/37）为0分，64.86%（24/37）为1分。结论 PET/MRI诊断胰腺癌的敏感度、特异度、图像融合匹配度及图像质量均与PET/CT相近，而其诊断准确率高于PET/CT，有助于诊断及鉴别胰腺占位性病变。

英文摘要:

Objective To compare the value of ¹⁸F-FDG PET/CT and PET/MRI for diagnosing space-occupying pancreatic lesions. Methods Data of 34 patients with space-occupying pancreatic lesions who underwent whole-body ¹⁸F-FDG PET/CT and upper abdominal MR examination were retrospectively analyzed. The nature of lesions, image fusion matching degree, image quality and additional information of ¹⁸F-FDG PET/CT and PET/MRI were observed and compared, and the values of diagnosing space-occupying pancreatic lesions were assessed. Results Totally 37 lesions were detected in 34 patients. PET/CT diagnosed 7 benign lesions and 30 malignant ones, the sensitivity, specificity and accuracy of PE/CT for diagnosing pancreatic cancer was 95.83%, 46.15% and 78.38%, respectively. PET/MRI diagnosed 11 benign lesions and 26 malignant ones, the sensitivity, specificity and accuracy was 100%, 84.61% and 94.59%, respectively. The diagnostic accuracy of PET/MRI was significantly higher than that of PET/CT (χ²=4.16, P=0.04). There was no significant difference of image fusion matching degrees between PET/CT and PET/MRI (P>0.05), nor of image quality among CT, MRI, PET/CT and PET/MRI (P>0.05). The additional image information score of 27.03% (10/37)lesions was -1, of 8.11% (3/37) was 0, while of 64.86% (24/37) was 1. Conclusion The sensitivity and specificity for diagnosing pancreatic cancer, image fusion matching degree and image quality of PET/MRI were similar to those of PET/CT, while the diagnostic accuracy of PET/MRI was higher than that of PET/CT, hence being helpful for diagnosing and differential space-occupying pancreatic lesions.

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