| 罗玲玲,汪世存,姚晓波,金晓毛,张然,夏俊勇,卞岍雨.分化型甲状腺癌术后患者131I治疗后全身显像中肝脏弥漫性摄取的临床意义[J].中国医学影像技术,2021,37(7):1020~1024 |
| 分化型甲状腺癌术后患者131I治疗后全身显像中肝脏弥漫性摄取的临床意义 |
| Clinical significances of diffuse liver uptake in 131I post-therapy whole body imaging of patients with differentiated thyroid carcinoma after surgical resection |
| 投稿时间：2020-04-07 修订日期：2021-03-01 |
| DOI：10.13929/j.issn.1003-3289.2021.07.013 |
| 中文关键词: 甲状腺肿瘤 放射性核素显像 肝脏弥漫性摄取 |
| 英文关键词:thyroid neoplasms radionuclide imaging diffuse liver uptake |
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| 中文摘要: |
| 目的 探讨分化型甲状腺癌（DTC）术后患者131I治疗后全身显像（Rx-WBS）中肝脏弥漫性摄取（DHU）的临床意义。方法 回顾性分析178例DTC，根据Rx-WBS所示DHU程度将其分为G0组（n=41）、G1组（n=69）、G2组（n=56）和G3组（n=12）；将P<0.2的因素纳入有序Logistic回归分析，筛选DHU影响因素。结果 178例DTC中，137例（137/178，76.97%）可见DHU。单因素分析显示4组患者促甲状腺激素（TSH）、131I剂量及远处转移（M）差异均有统计学意义（P均<0.05），而年龄、甲状腺球蛋白（Tg）等11个因素差异均无统计学意义（P均>0.05）。多因素有序Logistic回归分析显示131I剂量（β=0.013，P=0.036）是DHU程度的独立影响因素；4组间TSH、M、治疗次数及Tg差异均无统计学意义（P均>0.05）。结论 131I剂量是DHU程度的独立影响因素，且具有显著正向影响。 |
| 英文摘要: |
| Objective To explore the clinical significance of diffuse hepatic uptake (DHU) in 131I post-therapy whole body scan (Rx-WBS) of patients with differentiated thyroid carcinoma (DTC) after surgical resection. Methods Data of 178 DTC patients after surgical resection were retrospectively analyzed. According to the degrees of DHU in Rx-WBS, the patients were divided into group G0 (n=41), group G1 (n=69), group G2 (n=56) and group G3 (n=12), respectively. The factors with P<0.2 were put into orderly Logistic regression analysis to explore the impact factors of the degrees of DHU. Results Totally 137 patients (137/178, 76.97%) were found with DHU. Single factor analysis showed that there were significant differences of thyroid stimulating hormone (TSH), 131I dose and distant metastases (M) among 4 groups (all P<0.05), but not of age, thyroglobulin (Tg) nor other 11 factors (all P>0.05). Orderly Logistic regression analysis showed that 131I dose (β=0.013, P=0.036) was an independent impact factor of DHU degree, while no statistical difference of TSH, M, times of treatment nor Tg was detected (all P>0.05). Conclusion 131I dose was an independent impact factor of DHU degree, which had significant positive effect on the degree of DHU. |
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