| 付明翠,王颖,李慧君,朱美娇,王树杰,冯章志,杨明.相位对比电影MR成像评估婴幼儿脑血流特点[J].中国医学影像技术,2021,37(4):512~516 |
| 相位对比电影MR成像评估婴幼儿脑血流特点 |
| Phase contrast cine MRI evaluation on characteristics of cerebral blood flow in infants and young children |
| 投稿时间：2020-03-08 修订日期：2021-02-27 |
| DOI：10.13929/j.issn.1003-3289.2021.04.008 |
| 中文关键词: 脑血管循环 婴儿 磁共振成像 相位对比电影 |
| 英文关键词:cerebrovascular circulation infant magnetic resonance image phase contrast cine |
| 基金项目:江苏省"六大人才高峰"项目（LGY2019009）。 |
|
| 摘要点击次数: 2573 |
| 全文下载次数: 846 |
| 中文摘要: |
| 目的 采用相位对比电影MR成像（PC cine MRI）观察婴幼儿颈内动脉（ICA）血流动力学特点，评估脑血流量（CBF）。方法 对37例婴幼儿行MR检查，以多个编码流速度PC cine MR序列测量ICA峰值流速（Vp）及血流量，计算单位体积CBF。采用Pearson线性相关分析观察周龄与ICA Vp、ICA血流量、ICA直径、CBF及大脑体积之间以及ICA Vp与ICA直径、心率之间的关系。结果 周龄与ICA Vp无明显相关（P=0.532），与ICA血流量、ICA直径、CBF及大脑体积均呈正相关，与心率呈负相关（P均<0.01）。周龄与CBF的拟合曲线中，三次多项式的R2最高（R2=0.612）。ICA Vp与ICA直径、心率均无明显相关（P均>0.05）。结论 采用PC cine MRI能无创观察婴幼儿颈内动脉血流动力学特点，可为量化评估婴幼儿脑发育情况提供更多信息。 |
| 英文摘要: |
| Objective To observe the hemodynamics of the internal carotid artery (ICA) of infants and young children with phase contrast cine MRI (PC cine MRI), and to evaluate their cerebral blood flow (CBF). Methods Data of 37 infants and young children who underwent MR examination were retrospective analyzed. The peak velocity (VP) and blood flow of ICA were measured using PC cine MR sequences with multiple velocity encodings, and unit volume CBF was calculated. The relationships between age (weeks) and ICA VP, ICA blood flow, ICA diameter, CBF and brain volume, as well as between ICA VP and ICA diameter, heart rate were analyzed with Pearson linear correlation. Results Age was found positively correlated with ICA blood flow, ICA diameter, CBF and brain volume (all P<0.01), negatively correlated with heart rate (P<0.01),but not correlated with ICA VP (P=0.532).Among the fitting curves of age and CBF, R2 of cubic polynomial was the highest (R2=0.612). There was no significant correlation of ICA Vp and ICA diameter, nor between ICA Vp and heart rate (both P>0.05). Conclusion PC cine MRI could be used to non-invasively observe the hemodynamics of ICA of infants and young children, providing information for quantitative evaluation on brain development. |
| 查看全文 查看/发表评论 下载PDF阅读器 |
|
|
|
