邓国瑜,马亦龙,赵昌.药物洗脱微球经导管动脉化疗栓塞术治疗肝细胞癌进展[J].中国医学影像技术,2020,36(11):1730~1733 |
药物洗脱微球经导管动脉化疗栓塞术治疗肝细胞癌进展 |
Progresses of drug-eluting bead transcatheter arterial chemoembolization for treatment of hepatocellular carcinoma |
投稿时间:2019-08-11 修订日期:2020-11-19 |
DOI:10.13929/j.issn.1003-3289.2020.11.033 |
中文关键词: 癌,肝细胞 化学栓塞,治疗性 |
英文关键词:carcinoma, hepatocellular chemoembolization, therapeutic |
基金项目:广西医疗卫生适宜技术开发推广应用项目(S2017092)、广西壮族自治区卫生健康委员会自筹经费科研课题(Z20190664)。 |
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中文摘要: |
肝细胞癌(HCC)是最常见的原发性肝癌之一。经导管动脉化疗栓塞术(TACE)一直被用为中期HCC患者的一线治疗方法,而药物洗脱微球TACE(DEB-TACE)的临床应用近年来亦不断增加。本文对DEB-TACE的药物代谢动力学、微球选择、适应证和禁忌证及疗效评估进展进行综述。 |
英文摘要: |
Hepatocellular carcinoma (HCC) is one of the most common primary liver carcinoma. Transcatheter arterial chemoembolization (TACE) has been used as the first-line treatment for patients with mid-term HCC. In recent years,clinical application of drug-eluting bead TACE (DEB-TACE) kept increasing. The pharmacokinetics, selection of microspheres, indications, contraindications and evaluation on therapeutic effect of DEB-TACE for treatment of HCC were reviewed in this article. |
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