| 丁新华,王海军,王道英,王茸,么坤.SPECT/CT肺灌注显像评价肺动脉球囊扩张成形术治疗慢性血栓栓塞性肺动脉高压效果[J].中国医学影像技术,2020,36(7):1022~1026 |
| SPECT/CT肺灌注显像评价肺动脉球囊扩张成形术治疗慢性血栓栓塞性肺动脉高压效果 |
| SPECT/CT pulmonary perfusion imaging in evaluating efficacy of pulmonary balloon dilatation for treatment of chronic thromboembolic pulmonary hypertension |
| 投稿时间：2019-06-19 修订日期：2019-12-31 |
| DOI：10.13929/j.issn.1003-3289.2020.07.019 |
| 中文关键词: 肺栓塞 高血压,肺性 正电子发射断层显像 体层摄影术,X线计算机 血管成形术,球囊 |
| 英文关键词:pulmonary embolism hypertension, pulmonary positron-emission tomography tomography, X-ray computed angioplasty, balloon |
| 基金项目:国家自然科学基金（81460072）、甘肃省自然科学基金（17JR5RA057）。 |
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| 摘要点击次数: 2015 |
| 全文下载次数: 779 |
| 中文摘要: |
| 目的 以SPECT/CT肺灌注显像评价肺动脉球囊扩张成形术（BPA）治疗慢性血栓栓塞性肺动脉高压（CTEPH）的疗效。方法 对18例CTEPH患者分别于BPA前及其后1~3个月内行SPECT/CT肺灌注显像，以经导管肺动脉造影为标准，评价BPA前、后SPECT/CT探测肺段灌注缺损及灌注改善情况。结果 SPECT/CT肺灌注显像在BPA前探测肺段灌注缺损的敏感度、特异度、准确率、阳性预测值（PPV）及阴性预测值（NPV）分别为90.42%（302/334）、99.05%（418/422）、95.24%（720/756）、98.69%（302/306）及92.89%（418/450）；BPA后探测灌注改善的敏感度、特异度、准确率、PPV和NPV分别为77.78%（56/72）、80.00%（24/30）、78.43%（80/102）、90.32%（56/62）及60.00%（24/40）。结论 SPECT/CT肺灌注显像用于评价BPA治疗CTEPH后肺段灌注及改善具有较好临床价值。 |
| 英文摘要: |
| Objective To explore the efficacy of SPECT/CT pulmonary perfusion imaging for evaluation on therapeutic effect of balloon dilatation (BPA) for chronic thromboembolic pulmonary hypertension (CTEPH). Methods A total of 18 patients with CTEPH underwent SPECT/CT pulmonary perfusion imaging before and 1-3 months after BPA. Perfusion defect and perfusion improvement were observed before and after BPA taken catheter pulmonary angiography as standards. Results The sensitivity, specificity, accuracy, positive predictive value (PPV) and negative predictive value (NPV) of SPECT/CT pulmonary perfusion imaging in detecting pulmonary perfusion defect was 90.42%(302/334), 99.05%(418/422), 95.24%(720/756), 98.69%(302/306), 92.89%(418/450), respectively before BPA, while perfusion improvement after BPA was 77.78%(56/72), 80.00%(24/30), 78.43%(80/102), 90.32%(56/62) and 60.00%(24/40), respectively. Conclusion SPECT/CT pulmonary perfusion imaging has good clinical value in evaluating pulmonary segment perfusion and improvement in patients with CTEPH after BPA. |
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