| 莫纯威,黄晓新,金观桥,苏丹柯.表皮生长因子受体靶向治疗分子影像研究进展[J].中国医学影像技术,2020,36(5):767~771 |
| 表皮生长因子受体靶向治疗分子影像研究进展 |
| Advances in molecular imaging of epidermal growth factor receptor targeted therapy |
| 投稿时间：2019-06-24 修订日期：2020-05-12 |
| DOI：10.13929/j.issn.1003-3289.2020.05.032 |
| 中文关键词: 肿瘤 受体,表皮生长因子 正电子发射断层显像 体层摄影术,X线计算机 分子成像 |
| 英文关键词:neoplasms receptor,epidermal growth factor positron-emission tomography tomography,X-ray computed molecular imaging |
| 基金项目:国家自然科学基金（81760533）。 |
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| 中文摘要: |
| 表皮生长因子受体（EGFR）靶向治疗癌症需要准确评估肿瘤EGFR表达。分子影像技术以分子探针与细胞特定靶分子结合，通过PET/CT检测技术获取图像，可无创、准确、重复地实时评价靶分子表达。本文围绕PET各类EGFR分子探针研究进展进行综述。 |
| 英文摘要: |
| Targeted therapy of cancer with epidermal growth factor receptor (EGFR) requires accurate estimation of EGFR expression in tumors. Molecular image is a molecular probe binds to a specific target molecule of a cell and detected by PET/CT, which can be used to evaluate the expression of the target molecule non-invasively, repeatedly in real time. The research advances of various EGFR molecular probes for PET were reviewed in this article. |
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