| 田序伟,马爱琳,董家科,杨泽宏,沈君.胰腺腺鳞癌和导管腺癌影像学及病理学表现[J].中国医学影像技术,2020,36(5):712~715 |
| 胰腺腺鳞癌和导管腺癌影像学及病理学表现 |
| Comparison on imaging and pathological features of adenosquamous carcinoma of pancreas and invasive ductal adenocarcinoma of pancreas |
| 投稿时间：2019-05-07 修订日期：2020-01-15 |
| DOI：10.13929/j.issn.1003-3289.2020.05.017 |
| 中文关键词: 胰腺肿瘤 腺癌 癌,鳞状细胞 诊断,鉴别 体层摄影术,X线计算机 磁共振成像 |
| 英文关键词:pancreatic neoplasms adenocarcinoma carcinoma,squamous cell diagnosis,differential tomography,X-ray computed magnetic resonance imaging |
| 基金项目:新疆维吾尔自治区天山青年计划项目（2018Q056）。 |
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| 中文摘要: |
| 目的 对比观察胰腺腺鳞癌（ASqC）与胰腺浸润性导管腺癌（IDAC）的影像学及病理学表现。方法 回顾性分析经手术病理证实的11例ASqC（ASqC组）和22例IDAC（IDAC组）临床资料、CT、MRI表现及病理特征。比较分析2组影像学（病灶位置、大小、形态、中心坏死、强化峰值时间、胆管扩张、主胰管扩张）及病理表现（神经束受侵、淋巴结转移、脉管癌栓、Ki-67）的差异。结果 2组病灶CT所示直径、形态、中心坏死、强化峰值时间差异均有统计学意义（χ2=7.34，6.82，10.25，5.57，P均<0.05）。MRI示2组病灶T1WI及动态增强信号无显著差异，但IDAC组病灶T2WI信号低于ASqC组。病理结果显示ASqC组出现脉管癌栓比例（5/11，45.45%）高于IDAC组（2/22，9.09%，χ2=5.80，P=0.02）。结论 ASqC与IDAC影像学及病理学表现具有一定特异性，结合临床有助于鉴别诊断。 |
| 英文摘要: |
| Objective To comparatively analyze CT, MRI and pathological findings of adenosquamous carcinoma of pancreas (ASqC) and invasive ductal adenocarcinoma of pancreas (IDAC). Methods Clinical, imaging and pathological data of 11 patients with ASqC (ASqC group) and 22 with IDAC (IDAC group) confirmed with pathology were retrospectively analyzed. The differences of imaging findings (lesion location, size, morphology, central necrosis, peak enhancement time, bile duct dilatation, main pancreatic duct dilatation) and pathological features (nerve tract invasion, lymph node metastasis, vascular tumor emboli, Ki-67) were compared between 2 groups. Results CT showed significant differences in lesions' diameter, morphology, central necrosis and peak enhancement time between 2 groups (χ2=7.34, 6.82, 10.25, 5.57, all P<0.05). MRI showed that there was no significant difference of lesion's signal on T1WI and dynamic enhancement between 2 groups, while IDAC group had lower T2WI signals than ASqC group. Pathological results showed that the incidence of vascular tumor emboli in ASqC group (5/11, 45.45%) was higher than that in IDAC group (2/22, 9.09%, χ2=5.80, P=0.02). Conclusion ASqC and IDAC have certain pathological and imaging characteristics. Combination with clinical data is helpful to differential diagnosis. |
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