| 李正腾,王敏,潘冬梅,任佳忠,刘洪梅,李晴.双源CT测定甲状腺碘含量与甲状腺功能的相关性[J].中国医学影像技术,2020,36(4):610~613 |
| 双源CT测定甲状腺碘含量与甲状腺功能的相关性 |
| Dual-source CT evaluation on correlation between thyroid function and thyroid iodine concentration |
| 投稿时间：2019-08-26 修订日期：2020-03-16 |
| DOI：10.13929/j.issn.1003-3289.2020.04.033 |
| 中文关键词: 甲状腺 碘 体层摄影术,X线计算机 |
| 英文关键词:thyroid gland iodine tomography, X-ray computed |
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| 中文摘要: |
| 目的 采用双源CT测量成人甲状腺平均碘浓度、总碘含量，分析其与甲状腺功能的相关性，为评估机体碘营养状况及甲状腺功能提供依据。方法 采用双源CT对37例疑诊颈椎或颈部疾病患者行颈部双能量扫描，测量甲状腺组织平均碘浓度、体积，计算甲状腺总碘含量；检测其甲状腺功能[游离三碘甲状腺原氨酸（FT3）、总三碘甲状腺原氨酸（TT3）、游离甲状腺素（FT4）、总甲状腺素（TT4）及促甲状腺激素（TSH）]，分析成年人甲状腺平均碘浓度及总碘含量与甲状腺功能指标的相关性。结果 成人甲状腺组织平均碘浓度（1.34±0.47）mg/ml，甲状腺体积（12.64±3.98）ml，甲状腺总碘含量（16.62±7.69）mg。甲状腺总碘含量与FT3呈正相关（r=0.506，P均<0.05），而与TSH呈负相关（r=-0.326，P<0.05）；甲状腺平均碘浓度与FT3及TT3均呈正相关（r=0.461、0.363，P均<0.05）。结论 双源CT可测量甲状腺碘含量及碘浓度，有利于评估甲状腺功能及机体碘营养状况，为诊断及治疗甲状腺疾病提供参考；成年人甲状腺总碘含量与TSH呈负相关，而甲状腺总碘含量与FT3、甲状腺碘浓度与FT3及TT3均呈正相关。 |
| 英文摘要: |
| Objective To analyze the correlation of thyroid function and mean iodine concentration, total iodine of thyroid measured with dual-source CT, so as to provide a basis for assessment of iodine nutritional status and thyroid function. Methods Dual-energy scanning of neck was performed on 37 patients with suspected neck and cervical vertebrae disease using dual-source CT. The mean iodine concentration and the volume of thyroid gland were measured, then total thyroid iodine was calculated. The thyroid function[free triiodothyronine (FT3), free thyroxine (FT4), thyroid stimulating hormone (TSH), total triiodothyronine (TT3) and total thyroxine (TT4)] were tested. The correlations of the mean iodine concentration, total iodine of thyroid and thyroid function in adults were analyzed.Results The average iodine concentration, volume and total iodine content of thyroid tissue were (1.34±0.47)mg/ml, (12.64±3.98)ml and (16.62±7.69)mg in adult, respectively. The total iodine content of thyroid was positively correlated with FT3 (r=0.506, P<0.05), while negatively correlated with TSH (r=-0.326,P<0.05). The mean thyroid iodine concentration was positively correlated with FT3 or TT3 (r=0.461, 0.363, both P<0.05).Conclusion Dual-source CT can measure total iodine content and mean iodine concentration of thyroid, which is helpful to evaluating thyroid function and body iodine nutritional status and providing evidences for diagnosis and treatment of thyroid diseases. In adults, there are negative correlation of the total iodine content of thyroid and TSH, positive correlation of the total iodine content of thyroid and FT3, the mean thyroid iodine concentration and FT3 or TT3. |
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