| 王宇路,钱银锋.超极化13C MRI研究进展[J].中国医学影像技术,2020,36(2):303~306 |
| 超极化13C MRI研究进展 |
| Progresses of hyperpolarized 13C MRI |
| 投稿时间：2019-05-16 修订日期：2020-02-08 |
| DOI：10.13929/j.issn.1003-3289.2020.02.033 |
| 中文关键词: 分子探针 代谢 磁共振成像 |
| 英文关键词:molecular probes metabolism magnetic resonance imaging |
| 基金项目: |
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| 中文摘要: |
| “超极化”指通过动态核极化方法使原子核自旋极化达热平衡之上，以增强分子MRI信号。近年来，超极化MRI日益发展，可克服传统MR信号低、无法实时监测体内代谢过程的缺点，在检测肿瘤及其他疾病的代谢中显示出一定应用价值。本文就常用超极化13C生物探针、超极化MR设备及超极化13C MRI的研究进展进行综述，并对其发展趋势进行展望。 |
| 英文摘要: |
| The spin polarization of the nucleus is enhanced to improve molecular MR signal with dynamic nuclear polarization, which is called hyperpolarization. In recent years, the development of hyperpolarized MRI has overcome the disadvantages of low MRI signal and non-real-time monitoring of metabolic processes in vivo, and has showed certain value in detecting the metabolism of tumors and other diseases. The developments of hyperpolarized 13C biological probe, hyperpolarized MR devices and hyperpolarized 13C MRI were reviewed, and the developmental trend was prospected in this article. |
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