| 田士峰,刘爱连,陈安良,杨伟萍,鞠烨,宋清伟,姜艳.体素内不相干运动多模型参数鉴别Ⅰ期子宫内膜癌与子宫内膜息肉[J].中国医学影像技术,2019,35(12):1856~1860 |
| 体素内不相干运动多模型参数鉴别Ⅰ期子宫内膜癌与子宫内膜息肉 |
| Multiple model parameters of intravoxel incoherent motion in differentiation of stage Ⅰ endometrial carcinoma and endometrial polyp |
| 投稿时间：2019-01-28 修订日期：2019-09-29 |
| DOI：10.13929/j.1003-3289.201901178 |
| 中文关键词: 癌,子宫内膜样 息肉 磁共振成像 体素内不相干运动 |
| 英文关键词:carcinoma, endometrioid polyps magnetic resonance imaging intravoxel incoherent motion |
| 基金项目:首都科技领军人才培养工程（Z181100006318003）。 |
|
| 摘要点击次数: 2166 |
| 全文下载次数: 715 |
| 中文摘要: |
| 目的 探讨体素内不相干运动（IVIM）多模型参数对I期子宫内膜癌（EC）与子宫内膜息肉（EP）的鉴别价值。方法 回顾性分析经病理证实的31例I期EC患者（EC组）及14例EP患者（EP组）的临床及影像资料，患者术前均行1.5T MR检查，含IVIM序列（b=0、20、50、100、150、200、400、800、1 200、2 000、3 000 s/mm2）。测量并比较2组间病灶的IVIM多模型参数值，包括标准表观扩散系数（ADC-stand）、慢速表观扩散系数（ADC-slow）、快速表观扩散系数（ADC-fast）、灌注分数（f）、扩散分布指数（DDC）及拉伸指数（α）。采用ROC曲线评估IVIM参数对I期EC与EP的鉴别诊断效能。结果 EC组ADC-stand值、ADC-slow值、f值、DDC值及α值均小于EP组，ADC-fast值大于EP组，差异均有统计学意义（P均=0.001）。ROC曲线结果显示，ADC-stand值、ADC-slow值、ADC-fast值、f值、DDC值及α值对I期EC与EP均有鉴别诊断价值，AUC分别为0.885、0.877、0.919、0.926、0.906、0.902（P均<0.05）。结论 IVIM序列多模型参数能够有效鉴别I期EC与EP。 |
| 英文摘要: |
| Objective To investigate the value of the multiple model parameters of intravoxel incoherent motion (IVIM) in identification of stage Ⅰ endometrial carcinoma (EC) and endometrial polyp (EP). Methods The clinical and imaging data of 31 patients with stage Ⅰ EC (group EC) and 14 patients with EP (group EP), confirmed by postoperative pathological examination, were retrospectively analyzed, all patients were performed on 1.5T MR (including IVIM sequence, b=0, 20, 50, 100, 150, 200, 400, 800, 1 200, 2 000, 3 000 s/mm2) before operation. The IVIM multi-model parameter values of the lesions were measured and compared between the two groups, including the standard apparent diffusion coefficient (ADC-stand), slow-apparent diffusion coefficient (ADC-slow), fast-apparent diffusion coefficient (ADC-fast), perfusion fraction (f), distributed diffusion coefficient (DDC) and water molecular diffusion heterogeneity index (α). The ROC curve was used to evaluate the differential diagnostic efficacy of IVIM parameters for stage Ⅰ EC and EP. Results The ADC-stand value, ADC-slow value, f-value, DDC value and α value of the EC group were all less than the EP group, and the ADC-fast value was greater than the EP group (all P=0.001). ROC curve results showed the standard ADC value, ADC-slow value, ADC-fast value, f value, DDC value and α value had differential diagnostic value for stage Ⅰ EC and EP, the AUC was 0.885, 0.877, 0.919, 0.926, 0.906 and 0.902, respectively (all P<0.05). Conclusion The multi-model parameters of IVIM sequence can effectively identify stage Ⅰ EC and EP. |
| 查看全文 查看/发表评论 下载PDF阅读器 |
|
|
|
