| 彭玲,朱芳,丁明岩,张慧慧,赵含章,冀威,李颖.三维斑点追踪技术评价冠状动脉病变严重程度[J].中国医学影像技术,2019,35(5):677~681 |
| 三维斑点追踪技术评价冠状动脉病变严重程度 |
| 3D speckle tracking imaging in evaluating severity of coronary artery disease |
| 投稿时间：2018-10-08 修订日期：2019-03-12 |
| DOI：10.13929/j.1003-3289.201810024 |
| 中文关键词: 冠状动脉疾病 斑点追踪成像 冠状血管造影术 超声检查 |
| 英文关键词:coronary artery disease speckle tracking imaging coronary angiography ultrasonography |
| 基金项目:辽宁省自然科学基金计划重点项目（20170540542）。 |
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| 中文摘要: |
| 目的 探讨三维斑点追踪成像（3D-STI）技术评价冠状动脉粥样硬化性心脏病（简称冠心病）患者冠状动脉病变程度的价值。方法 收集103例疑似冠心病患者，参考冠状动脉造影结果，根据冠状动脉Gensini评分，将其分为病变组（n=79）和正常组（Gensini评分0分，n=24），病变组又分为轻度（Gensini评分<25分，n=40）、中度（Gensini评分25~50分，n=26）和重度（Gensini评分>50分，n=13）3个亚组。应用3D-STI技术获得左心室三维整体纵向应变（3D-GLS）、三维整体周向应变（3D-GCS）、三维整体面积应变（3D-GAS）和三维整体径向应变（3D-GRS），比较2组间和3个亚组间的差异。绘制ROC曲线，评价3D-STI参数评价冠状动脉正常或轻度病变（Gensini评分<25分）与中重度病变（Gensini评分≥25分）的效能。结果 病变组3D-GLS、3D-GCS、3D-GAS及3D-GRS均低于正常组（P均<0.05）。病变组内轻度、中度与重度亚组间各应变参数总体差异均有统计学意义（P均<0.05）。ROC曲线结果显示，AUC由大到小依次为3D-GLS（0.929）、3D-GCS（0.873）、3D-GRS（0.853）和3D-GAS（0.819）。结论 3D-STI技术用于评价冠心病患者冠状动脉病变严重程度具有一定价值。 |
| 英文摘要: |
| Objective To explore the value of 3D speckle tracking imaging (3D-STI) in evaluating the degree of coronary artery disease in patients with coronary artery disease. Methods Totally 103 patients with suspected coronary artery disease were enrolled. According to the coronary angiography results and Gensini score, the patients were divided into lesion group (n=79) and normal group (Gensini score=0, n=24). Patients in lesion group were then divided into mild subgroup (Gensini score <25, n=40), moderate subgroup (Gensini score 25-50, n=26) and severe subgroup (Gensini score >50, n=13). 3D global longitudinal strain (3D-GLS), 3D global circumferential strain (3D-GCS), 3D global area strain (3D-GAS) and 3D radial strain (3D-GRS) were obtained using 3D-STI and compared between the two groups and among the three subgroups. ROC curve was drawn, and the efficacy of 3D-STI parameters were evaluated for the normal or mild coronary lesions (Gensini score <25) and moderate to severe lesions (Gensini score ≥ 25). Results 3D-GLS, 3D-GCS, 3D-GAS and 3D-GRS in the lesion group were lower than those in the normal group (all P<0.05). There were significant differences in the overall strain parameters among the mild, moderate and severe subgroups in the lesion group (all P<0.05). ROC curve results showed that AUC decreased from 3D-GLS (0.929), 3D-GCS (0.873), 3D-GRS (0.853) to 3D-GAS (0.819). Conclusion 3D-STI has certain value in evaluating the severity of coronary artery disease in patients with coronary artery disease. |
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