于阳,杨旗,杨晓旭,吴芳,齐志刚,卢洁.基于DANTE预脉冲SPACE MR序列定量评价蛛网膜颗粒[J].中国医学影像技术,2019,35(4):592~595
基于DANTE预脉冲SPACE MR序列定量评价蛛网膜颗粒
DANTE prepulse SPACE MR sequence in quantitative evaluation of arachnoid granules
投稿时间:2018-10-18  修订日期:2019-01-08
DOI:10.13929/j.1003-3289.201810095
中文关键词:  蛛网膜颗粒  磁共振成像  延迟交变章动调整激发
英文关键词:arachnoid granulations  magnetic resonance imaging  delay alternating with nutation for tailored excitation
基金项目:国家自然科学基金优秀青年科学基金项目(81522021)、国家重点研发计划(2016YFC1301702、2016YFC0107107)、北京市医院管理局"登峰"计划专项(DFL20180802)。
作者单位E-mail
于阳 首都医科大学宣武医院 放射科, 北京 100053
磁共振成像脑信息学北京市重点实验室, 北京 100053 
 
杨旗 首都医科大学宣武医院 放射科, 北京 100053
磁共振成像脑信息学北京市重点实验室, 北京 100053 
 
杨晓旭 首都医科大学宣武医院 放射科, 北京 100053
磁共振成像脑信息学北京市重点实验室, 北京 100053 
 
吴芳 首都医科大学宣武医院 放射科, 北京 100053
磁共振成像脑信息学北京市重点实验室, 北京 100053 
 
齐志刚 首都医科大学宣武医院 放射科, 北京 100053
磁共振成像脑信息学北京市重点实验室, 北京 100053 
 
卢洁 首都医科大学宣武医院 放射科, 北京 100053
磁共振成像脑信息学北京市重点实验室, 北京 100053 
imaginglu@hotmail.com 
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中文摘要:
      目的 评价基于DANTE预脉冲SPACE定量评价蛛网膜颗粒的价值。方法 纳入头颅影像学检查证实存在蛛网膜颗粒的30例患者,分别进行SPACE序列成像和基于DANTE预脉冲的SPACE序列成像。评价SPACE序列图像和DANTE-SPACE序列图像中静脉窦内和颅板下蛛网膜颗粒分布特征,并进行定量测量,包括最大横截面积、最长径、SNR和CNR。比较两种方法获得各测量指标的统计学差异。结果 采用SPACE序列发现43个蛛网膜颗粒,位于静脉窦内29个,颅板下14个;DANTE-SPACE序列检出45个蛛网膜颗粒,其中位于静脉窦内31个,颅板下14个。SPACE和DANTE-SPACE序列显示蛛网膜颗粒分布特征差异无统计学意义(χ2=0.155,P=0.997)。SPACE和DANTE-SPACE序列测量静脉窦腔内蛛网膜颗粒最大横截面积[(32.55±17.08) mm2,(29.15±16.24) mm2]、最长径[(7.13±2.00) mm,(6.42±1.81) mm]、SNR (88.82±29.57,83.30±32.11)、CNR (45.99±28.57,65.33±30.96)差异均有统计学意义(P均<0.05),测量颅板下蛛网膜颗粒最大横截面积[(21.62±9.01) mm2,(21.83±9.04) mm2]、最长径[(6.74±2.83) mm,(6.66±2.87) mm]、SNR (86.91±35.48,76.82±36.20)、CNR (16.87±6.32,20.07±12.76)差异均无统计学意义(P均>0.05)。结论 基于DANTE预脉冲SPACE序列可有效抑制静脉窦内的慢血流伪影,更精准地显示蛛网膜颗粒。
英文摘要:
      Objective To explore the value of delay alternating with nutation for tailored excitation (DANTE)-sampling perfection with application optimized contrast using different flip-angle evolution (SPACE) sequences in quantitative evaluation of arachnoid granules (AG). Methods Thirty patients with arachnoid granules confirmed by conventional imaging were enrolled. All patients underwent SPACE and DANTE-SPACE sequences scanning. Distribution characteristics of arachnoid particles in sinus cavities and cranial plate on SPACE and DANTE-SPACE sequence images were evaluated, and the measurements were performed and statistically analyzed, including maximum cross-sectional area, longest diameter, SNR and CNR. Results A total of 43 arachnoid particles were detected with SPACE sequence, 29 in the sinus cavities and 14 in the cranial plate, while 45 arachnoid particles were found with DANTE-SPACE, 31 in the sinus cavities and 14 in the cranial plate. SPACE and DANTE-SPACE sequences showed no statistically significant difference in distribution of arachnoid particles (χ2=0.155, P=0.997). In the sinus cavity, SPACE and DANTE-SPACE sequences showed significant differences of the maximum cross-sectional area ([32.55±17.08]mm2,[29.15±16.24]mm2), the longest diameter ([7.13±2.00]mm,[6.42±1.81]mm), SNR (88.82±29.57, 83.30±32.11) and CNR (45.99±28.57, 65.33±30.96) of arachnoid particles (all P<0.05), but no statistical difference was found in maximum cross-sectional area ([21.62±9.01]mm2 and[21.83±9.04]mm2), longest diameter ([6.74±2.83)mm,[6.66±2.87]mm), SNR(86.91±35.48, 76.82±36.20) nor CNR(16.87±6.32, 20.07±12.76) in the cranial plate (all P>0.05). Conclusion DANTE-SPACE can effectively inhibit slow blood flow artifacts in the sinus, and accurately display arachnoid particles.
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