| 蒋丽萍,周爱云,余美琴.CEUS鉴别诊断涎腺良恶性病变[J].中国医学影像技术,2019,35(4):521~525 |
| CEUS鉴别诊断涎腺良恶性病变 |
| Differential diagnosis of CEUS in salivary malignant and benign lesions |
| 投稿时间：2018-10-10 修订日期：2019-01-11 |
| DOI：10.13929/j.1003-3289.201810040 |
| 中文关键词: 涎腺肿瘤 造影剂 超声检查 |
| 英文关键词:salivary gland neoplasms contrast media ultrasonography |
| 基金项目:江西省卫生计生委科技计划（20175130）。 |
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| 中文摘要: |
| 目的 探讨CEUS对涎腺良恶性病变的鉴别诊断价值。方法 对87例涎腺病变患者进行CEUS检查，其中良性肿瘤74例，恶性肿瘤13例，观察肿块的增强均匀程度、增强模式、增强边界、增强环和增强后肿块范围，根据肿块及周边腺体组织的时间-强度曲线分析肿块的增强程度、达峰方式和消退方式。比较涎腺良恶性肿瘤间的差异。结果 涎腺良恶性病变间增强程度、增强模式、增强均匀程度、达峰方式及消退方式的差异均无统计学意义（P均 ≥ 0.05），两者间增强边界、增强环及增强后肿块范围差异均有统计学意义（P均<0.01）。联合应用增强边界、增强环及增强后肿块范围，其鉴别诊断涎腺良恶性病变的敏感度、特异度和准确率为84.62%（11/13）、95.95%（71/74）和94.25%（82/87）。结论 涎腺恶性病变CEUS的主要特征是增强后无完整增强环、增强边界不清、增强后肿块范围增大，三者联合应用对涎腺良恶性病变具有较高的诊断效能。 |
| 英文摘要: |
| Objective To explore the differential diagnostic value of CEUS in salivary malignant and benign lesions. Methods Totally 87 lesions (including 74 benign lesions and 13 malignant lesions) underwent CEUS, then the degree of homogeneous, enhancement type, margin, rim and enlarged area were observed and analyzed respectively. In addition, the enhancement degree, type of enter-in and wash-out were analyzed according to the time-intensity curves of lesions and surrounding glands. The differences between benign and malignant lesions were compared. Results The enhancement degree, enhancement type, degree of homogeneous, type of wash-in and wash-out had no statistically significant differences between benign and malignant lesions (all P ≥ 0.05), while the enhancement margin, rim and enlarged enhancement area showed statistically significant differences between them (all P<0.01). Combining the latter three features, the differential diagnostic sensitivity, specificity and accuracy was 84.62% (11/13), 95.95% (71/74) and 94.25% (82/87), respectively. Conclusion The absent enhancement rim, ill-defined margin and enlarged enhancement area are features of salivary malignant lesions, and combining all of them has the great differentiated diagnostic efficacy to salivary malignant lesions. |
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