| 李进丹,许泽艳,王瑞,杨军,廖承德.聚焦超声在脑部疾病的应用进展[J].中国医学影像技术,2019,35(3):439~442 |
| 聚焦超声在脑部疾病的应用进展 |
| Progresses of focused ultrasound in brain diseases |
| 投稿时间：2018-07-03 修订日期：2018-12-05 |
| DOI：10.13929/j.1003-3289.201807015 |
| 中文关键词: 血脑屏障 聚焦超声 脑部疾病 |
| 英文关键词:blood-brain barrier focused ultrasound brain diseases |
| 基金项目:国家自然科学基金（81260408、81760316、81703155）。 |
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| 中文摘要: |
| 血脑屏障（BBB）阻碍多数治疗药物进入脑组织，导致临床诊治脑部疾病、特别是中枢神经系统疾病困难。借助微泡造影剂，聚焦超声可以无创、重复开放BBB。近年来国内外逐渐开展了聚焦超声治疗脑部疾病的实验和临床研究。本文就聚焦超声在脑部疾病的研究进展进行综述。 |
| 英文摘要: |
| The blood-brain barrier (BBB) prevents most therapeutic drugs from entering the brain tissue, which makes diagnosis and treatment of brain diseases difficult, especially diseases of central nervous system. Focused ultrasound can open BBB non-invasively and repeatedly by means of microbubble contrast agents. In recent years, experimental and clinical researches on focused ultrasound treatment of brain diseases have been carried out at home and abroad. The research progresses of focused ultrasound in brain diseases were reviewed in this article. |
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