| 戴望春,刘鸿圣,邝民伟,李玉琼,陈希文.儿童粒细胞肉瘤MRI表现及文献复习[J].中国医学影像技术,2019,35(3):408~411 |
| 儿童粒细胞肉瘤MRI表现及文献复习 |
| MRI features of childhood granulocytic sarcoma and literature review |
| 投稿时间：2018-08-21 修订日期：2019-01-07 |
| DOI：10.13929/j.1003-3289.201808144 |
| 中文关键词: 肉瘤,髓样 儿童 白血病 磁共振成像 |
| 英文关键词:sarcoma,myeloid child leukemia magnetic resonance imaging |
| 基金项目:广东省科技厅科技计划项目（2016ZC0227）、广州市科技计划项目（201804010142）。 |
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| 中文摘要: |
| 目的 观察儿童粒细胞肉瘤（GS）的MRI表现。方法 回顾性分析经病理确诊的4例GS患儿的MRI资料，观察肿瘤的位置、大小、形态、信号特点、骨质破坏情况及强化特点。结果 4例GS，3例为多发病变，1例单发。1例病灶位于T3~T7椎体水平椎管内硬膜外及椎旁、双侧上颌窦及蝶窦窦壁、眶周；1例位于L1~L2椎体水平椎管内硬膜外及椎旁；1例位于T2~T4、T10~T11椎体水平椎管内硬膜外及椎旁；1例位于T11~T12、L4~S2椎体水平椎管内硬膜外及椎旁、左侧眼眶、蝶骨及右侧额窦窦壁；均在局部形成软组织肿块或经椎间孔达椎管外形成椎旁肿块。3例骨髓信号受到弥漫性抑制。所有病灶的T1WI信号均较周围正常肌肉稍高，脂肪抑制T2WI均呈稍高信号，增强扫描后均呈轻中度均匀强化。2例椎体骨质破坏，表现为T1WI明显低信号，脂肪抑制T2WI明显高信号，增强扫描后明显均匀强化。结论 儿童GS的MRI表现具有一定特征性，有助于本病诊断。 |
| 英文摘要: |
| Objective To investigate the MRI findings of childhood granulocytic sarcoma (GS). Methods MRI data of 4 child patients with GS confirmed pathologically and immunohistochemistry were retrospectively analyzed. The location, size, morphology, signal characteristics, bone destruction and enhancement features of the tumor were observed. Results Among 4 patients, 3 cases were multiple, and 1 case was single. The lesion of 1 case was located in T3-T7 epidural intra-spinal canal and vertebral side, double side wall of maxillary sinus and sphenoid sinus, peri-orbit bone, of 1 case was located in L1-L2 epidural intra-spinal canal, of 1 case was located in T2-T4 and T10-T11 epidural intra-spinal canal, of 1 case was located in T11-T12 and L4-S2 level epidural intra-spinal canal, left side of the eye socket, sphenoid bone, and right side of the frontal sinus wall. Totally 4 cases were found soft tissue masses in the local or formed paravertebral lump through intervertebral foramen. The bone marrow signal of 3 cases was inhibited diffusely. MRI showed that T1WI signal slightly higher than normal surrounding muscles, while T2WI fat suppression showed slightly high signal intensity, and mild to moderate homogeneous enhancement. Two cases showed vertebral bone destruction, characterized by T1WI low signal obviously, T2WI fat suppression high signal obviously, and homogenous enhancement. Conclusion MRI features of GS of childhood have some characteristics, and they are helpful for diagnosis of GS. |
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