| 徐艳军,章鸣,谭宜,唐逵,周丹.彩色多普勒检测眼上静脉血流评估甲状腺相关性免疫眼眶病疗效[J].中国医学影像技术,2018,34(11):1650~1653 |
| 彩色多普勒检测眼上静脉血流评估甲状腺相关性免疫眼眶病疗效 |
| Color Doppler imaging of superior ophthalmic vein in evaluation on curative effect of thyroid related immune orbitopathy |
| 投稿时间：2018-02-22 修订日期：2018-08-07 |
| DOI：10.13929/j.1003-3289.201802089 |
| 中文关键词: 甲状腺 过敏和免疫 眼眶 眼上静脉 超声检查,多普勒,彩色 |
| 英文关键词:Thyroid gland Allergy and immunology Eyelids Superior ophthalmic vein Ultrasonography, Doppler, color |
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| 中文摘要: |
| 目的 探讨CDFI检测活动期甲状腺相关性免疫眼眶病（TRIO）患者治疗前后眼上静脉（SOV）血流速度变化特点。方法 对31例活动期TRIO患者（TRIO组）及24名正常对照组受试者的双眼SOV进行CDFI检查，记录其血流情况（正向、反向、未探及），并于血流频谱图测量SOV最大流速和最小流速。对活动期TRIO患者进行糖皮质激素（n=9）或眼眶减压术（n=22）治疗，治疗后6~14个月内复查。分析TRIO组治疗前后（治疗前亚组和治疗后亚组）及正常对照组血流参数间的差异。结果 TRIO患者治疗前后亚组和正常对照组间SOV血流情况总体差异有统计学意义（χ2=15.965，P=0.003）；SOV最大流速和最小流速总体差异均有统计学意义（P均<0.001），两两比较，TRIO治疗前亚组与正常对照组间、TRIO治疗前亚组与治疗后亚组间差异有统计学意义（P均<0.05），TRIO治疗后亚组与正常对照组间差异无统计学意义（P>0.05）。结论 活动期TRIO患者SOV血流速度显著下降，接受治疗后血流速度基本恢复正常；静脉淤血可能是导致TRIO进展的重要因素，治疗TRIO应注重改善眼眶的静脉充血淤滞状况。 |
| 英文摘要: |
| Objective To investigate the blood flow velocity changes of superior ophthalmic vein (SOV) using CDFI in patients with congestive thyroid related immune orbitopathy (TRIO) before and after treatment. Methods Totally 31 patients with TRIO and 24 normal controls were enrolled. CDFI was performed on both eyes of each subject. The blood flow (forward, reverse and not detected) and the spectrum of SOV were observed, and the maximum and minimum flow velocity were measured. TRIO patients were treated with corticosteroids (n=9) or orbital decompression (n=22), and CDFI was repeatedly performed 6-14 months after treatment. The differences of the blood flow parameters were analyzed among the groups of TRIO patients before and after treatment and the normal controls. Results There was significant difference of SOV blood flow among TRIO patients before, after treatment and normal controls (χ2=15.965, P=0.003). The overall differences of maximum and minimum SOV flow velocity were significant among the 3 groups (both P<0.001); compared in pairs, significant differences were found between the groups of TRIO patients before treatment and the normal controls, as well as TRIO patients before and after treatment (all P<0.05). No significant difference was found between TRIO patients after treatment and the normal controls (P>0.05). Conclusion SOV flow significantly reduces in patients with congestive TRIO before treatment and normalizes after treatment, suggesting that venous congestion plays a significant role in the disease progression. The treatment of TRIO should focus on improving orbital venous congestion. |
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