| 李林,史建国,董春华,刘勇,马常友,杨光勇,赵建设.3D高分辨MRI在局灶性皮质发育不良Ⅱ型患儿中的应用[J].中国医学影像技术,2018,34(11):1641~1644 |
| 3D高分辨MRI在局灶性皮质发育不良Ⅱ型患儿中的应用 |
| Application of 3D high-resolution MRI in children with focal cortical dysplasia type Ⅱ |
| 投稿时间：2018-01-02 修订日期：2018-08-06 |
| DOI：10.13929/j.1003-3289.201801008 |
| 中文关键词: 儿童 局灶性皮质发育不良 磁共振成像 |
| 英文关键词:Child Focal cortical dysplasia Magnetic resonance imaging |
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| 中文摘要: |
| 目的 探讨3D高分辨MR成像在儿童局灶性皮质发育不良（FCD）Ⅱ型中的应用价值。方法 回顾性分析18例经病理证实的FCD Ⅱ型患儿的MRI资料，观察灰白质分界模糊、局灶性皮质结构异常、灰白质信号以及transmantle征（皮层下白质内向脑室方向延伸的异常信号）等征象，计算并比较各序列对以上征象的检出率。结果 18例患儿中，15例存在MRI阳性征象，包括灰白质分界模糊14例（14/18，77.78%），局灶性皮质结构异常11例（11/18，61.11%），transmantle征10例（10/18，55.56%），白质信号异常11例（11/18，61.11%）及灰质信号异常13例（13/18，72.22%）。3D-T1WI对灰白质分界模糊、局灶性皮质结构异常、白质信号异常和灰质信号异常的检出率均高于常规T1WI（P=0.009、0.022、0.038、0.020）；3D-T2 FLAIR对灰白质分界模糊、局灶性皮质结构异常和灰质信号异常检出率高于T2 FLAIR序列（P=0.022、0.018、0.009）。结论 3D高分辨MR序列可提高对FCD Ⅱ型患儿的检出率，为术前评估提供更准确的信息。 |
| 英文摘要: |
| Objective To observe the application value of 3D high-resolution MRI in children with focal cortical dysplasia (FCD) of type Ⅱ. Methods MRI data of 18 children with FCD Ⅱ confirmed by pathology were retrospectively analyzed. The following MRI signs, including blurring of junction of the gray matter-white matter, abnormality of structure with focal cortex, gray matter and white matter signal, transmantle sign (the abnormal signal extending to the ventricle in subcortical white matter) were observed. Then the detection rates of the above MRI signs in each sequence were calculated and compared. Results In all of the 18 children, MRI abnormities were found in 15 children, including blurring of junction of the gray-white matter in 14 (14/18, 77.78%), the abnormality of structure with focal cortex in 11 (11/18, 61.11%), transmantle sign in 10 (10/18, 55.56%), the abnormality of white matter signal in 11 (11/18, 61.11%) and the abnormality of gray matter signal in 13 (13/18, 72.22%). The detection rates of 3D-T1WI were higher than those of T1WI for blurring of junction of the gray-white matter, abnormality of structure with focal cortex, the abnormality of white matter signal and the abnormality of gray matter signal (P=0.009, 0.022, 0.038, 0.020). The detection rates of 3D-T2 FLAIR were higher than those of T2 FLAIR sequence for the blurring of junction of the gray-white matter, abnormality of structure with focal cortex and the abnormality of gray matter signal (P=0.022, 0.018, 0.009). Conclusion 3D high-resolution MR sequences could improve the detection rate of FCD Ⅱ, therefore providing more accurate information for preoperative assessment. |
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