| 邱佳,唐乐梅,苗延巍,孙博.多发性硬化及视神经脊髓炎谱系疾病视觉通路损伤的光学相干断层扫描及MRI研究进展[J].中国医学影像技术,2018,34(10):1590~1594 |
| 多发性硬化及视神经脊髓炎谱系疾病视觉通路损伤的光学相干断层扫描及MRI研究进展 |
| Progresses of optical coherence tomography and MRI in visual pathway damage of multiple sclerosis and neuromyelitis optica spectrum disorders |
| 投稿时间：2018-01-30 修订日期：2018-06-19 |
| DOI：10.13929/j.1003-3289.201801184 |
| 中文关键词: 多发性硬化 视神经脊髓炎谱系疾病 体层摄影术,光学相干 磁共振成像 |
| 英文关键词:Multiple sclerosis Neuromyelitis optica spectrum disorder Tomography optical coherence Magnetic resonance imaging |
| 基金项目: |
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| 中文摘要: |
| 多发性硬化（MS）与视神经脊髓炎谱系疾病（NMOSD）的临床症状和影像学表现均具有相似性，但二者病理生理学机制和治疗方式各不相同，甚至某些针对MS的免疫治疗会加重NMOSD病情，早期准确鉴别诊断有助于改善患者预后。光学相干断层扫描（OCT）是一种非侵入性成像方法，已被广泛用于定量分析MS、NMOSD和其他疾病的视网膜损伤。MRI可显示MS、NMOSD患者特定视觉通路区域包括视神经、视交叉、视束、外侧膝状体、视放射和视觉皮层的病变，且MRI新技术还能定量分析MS和NMOSD的病灶特征。本文对OCT、MRI在MS及NMOSD中视觉通路损伤的研究进展进行综述。 |
| 英文摘要: |
| Multiple sclerosis (MS) and neuromyelitis optica spectrum disorder (NMOSD) have similarities in imaging and clinical manifestations. However, their pathophysiological mechanisms and treatment are different. Some immunotherapy for MS may lead to deterioration of NMOSD, therefore early accurate differential diagnosis of these two diseases will help to improve the prognosis. Optical coherence tomography (OCT) is a non-invasive imaging tool that has been used in MS, NMOSD and other diseases to quantify the damage of retina. MRI can be used to obtain pathology damage of visual pathway in MS and NMOSD, which includes the optic nerve, the optic chiasma, the optic tract, the lateral geniculate nucleus, the optic radiations and the visual cortex. In addition, using new techniques of MRI can quantify evaluate the characteristics of MS and NMOSD. The study progresses on the damage of visual pathway in NMOSD and MS with OCT and MRI were reviewed in this article. |
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