| 常红花,李杰,王亚魁,金笑,袁慧书.IDEAL-IQ技术定量测量健康青年女性颈部锁骨上脂肪[J].中国医学影像技术,2018,34(5):760~764 |
| IDEAL-IQ技术定量测量健康青年女性颈部锁骨上脂肪 |
| Quantitative measurement of supraclavicular adipose tissue in healthy young women with IDEAL-IQ technique |
| 投稿时间：2018-01-03 修订日期：2018-03-18 |
| DOI：10.13929/j.1003-3289.201801083 |
| 中文关键词: 锁骨上 脂肪组织 棕色脂肪 磁共振成像 |
| 英文关键词:Supraclavicular Adipose tissue Brown fat Magnetic resonance imaging |
| 基金项目: |
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| 中文摘要: |
| 目的 评估基于最小二乘法估计和不对称回波迭代分解的水脂分离（IDEAL-IQ）技术定量测量健康青年女性颈部锁骨上脂肪的可行性。方法 招募87名20~35岁健康青年女性，根据体质量指数（BMI）分为BMI<24 kg/m2组（n=72）和BMI ≥ 24 kg/m2组（n=15）。对受试者行IDEAL序列扫描，分别测量颈部锁骨上、胸壁、腹壁皮下脂肪及肝脏的脂肪分数（FF）及T2*弛豫率（R2*）值，比较两组间及锁骨上与胸壁皮下脂肪FF、R2*值的差异，并分析FF、R2*与BMI的相关性。结果 颈部锁骨上脂肪FF低于胸壁皮下脂肪FF值；锁骨上脂肪R2*值高于胸壁皮下脂肪R2*值。BMI<24 kg/m2组与BMI ≥ 24 kg/m2组间颈部锁骨上、胸壁皮下脂肪，腹壁、肝脏的FF、R2*值及颈部/胸壁FF值、颈部/胸壁R2*值差异均有统计学意义（P均<0.05）。颈部锁骨上脂肪FF值与BMI呈正相关（r=0.601，P<0.001），R2*值与BMI呈负相关（r=-0.409，P=0.001）。结论 MR IDEAL-IQ技术可定量测定颈部锁骨上与体部脂肪的差异，两者间FF及R2*值存在差别。 |
| 英文摘要: |
| Objective To assess the feasibility of quantitative measurement of subcutaneous and supraclavicular adipose tissue with iterative decomposition of water and fat with echo asymmetry and least square estimation-iron quantification sequence (IDEAL-IQ). Methods Totally 87 normal young female volunteers (20-35 years old) were recruited and divided into body mass index (BMI)<24 kg/m2 group (n=72) and BMI ≥ 24 kg/m2 group (n=15). Fat fraction (FF) and T2* relaxation rate (R2*) of supraclavicular adipose tissue, chest wall adipose tissue, abdominal wall adipose tissue and liver were measured, respectively. The differences of FF and R2* value of chest wall, subcutaneous and supraclavicular adipose tissue were compared between two groups, and the correlation between FF, R2* value of supraclavicular adipose tissue and BMI was respectively analyzed. Results FF of supraclavicular adipose tissue (%) was lower than that of chest wall subcutaneous adipose tissue (%, P<0.001). R2* of supraclavicular adipose tissue (Hz) was higher than that of chest wall subcutaneous adipose tissue (Hz, P<0.001). The differences of FF and R2* values of supraclavicular adipose tissue, chest wall, abdominal wall subcutaneous adipose tissue and liver were significant between BMI<24 kg/m2 group and BMI ≥ 24 kg/m2 group (all P<0.05). There was positive correlation (r=0.601, P<0.001) between FF of supraclavicular adipose tissue and BMI and negative correlation (r=-0.409, P=0.001) between R2* of supraclavicular adipose tissue and BMI. Conclusion IDEAL-IQ technique can quantitatively assess the difference between subcutaneous and supraclavicular adipose tissue in healthy young women. FF and R2* value has significant difference between the above mentioned positions. |
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