| 赵婷婷,闫斌.DWI鉴别子宫癌肉瘤与Ⅰ级子宫内膜样腺癌[J].中国医学影像技术,2018,34(5):734~738 |
| DWI鉴别子宫癌肉瘤与Ⅰ级子宫内膜样腺癌 |
| DWI differential diagnosis of uterine carcinosarcoma and grade Ⅰ endometrioid adenocarcinoma |
| 投稿时间：2017-08-01 修订日期：2018-03-17 |
| DOI：10.13929/j.1003-3289.201708001 |
| 中文关键词: 子宫肿瘤 癌肉瘤 癌,子宫内膜样 磁共振成像 扩散加权成像 |
| 英文关键词:Uterine neoplasms Carcinosarcoma Carcinoma, endometrioid Magnetic resonance imaging Diffusion weighted imaging |
| 基金项目: |
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| 中文摘要: |
| 目的 探讨ADC值及DWI相对信号强度（rSI）鉴别诊断子宫癌肉瘤与Ⅰ级子宫内膜样腺癌的价值。方法 经手术病理证实的13例子宫癌肉瘤和23例Ⅰ级子宫内膜样腺癌患者均接受常规MRI及DWI扫描，测量并比较2种肿瘤的平均ADC值（ADCmean）、最小ADC值（ADCmin）及rSI。结果 子宫癌肉瘤rSI（8.20±1.77）高于Ⅰ级子宫内膜样腺癌（6.95±2.19，P=0.04）。以rSI=7.42为临界值，rSI鉴别诊断子宫癌肉瘤与Ⅰ级子宫内膜样腺癌的ROC曲线下面积为0.71（P<0.05），敏感度、特异度和准确率分别为69.23%、60.87%和61.11%。子宫癌肉瘤与Ⅰ级子宫内膜样腺癌间ADCmean和ADCmin差异均无统计学意义（P均>0.05）。结论 ADC值鉴别诊断子宫癌肉瘤与Ⅰ级子宫内膜样腺癌的价值有限，DWI的rSI有助于鉴别。 |
| 英文摘要: |
| Objective To investigate the significance of ADC value and DWI relative signal intensity (rSI) in differential diagnosis of uterine carcinosarcoma and grade Ⅰ endometrioid adenocarcinoma (EA). Methods Totally 13 patients with uterine carcinosarcoma and 23 patients with grade Ⅰ EA which were all pathologically proved were enrolled. Conventional MRI and DWI were obtained in all 36 patients. The mean ADC values (ADCmean), minimum ADC values (ADCmin) and rSI were measured and compared between uterine carcinosarcoma and grade Ⅰ EA patients. Results The rSI of uterine carcinosarcoma (8.20±1.77) was significantly higher than that of grade Ⅰ EA (6.95±2.19, P=0.04). Taking rSI=7.42 as the diagnostic threshold, the area under the ROC curve was 0.71 (P<0.05), and the sensitivity, specificity, accuracy was 69.23%, 60.87% and 61.11%, respectively. However, there was no statistical difference of ADCmean and ADCmin between uterine carcinosarcoma and grade Ⅰ EA patients (both P>0.05). Conclusion ADC value is of limited significance in differential diagnosis of uterine carcinosarcoma and grade Ⅰ EA, whereas rSI is useful for the identification of these two diseases. |
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