| 程润田,陈莉,罗天友,龚军伟.DTI观察慢性丘脑梗死患者躯体感觉传导纤维继发性变性[J].中国医学影像技术,2018,34(5):646~649 |
| DTI观察慢性丘脑梗死患者躯体感觉传导纤维继发性变性 |
| DTI observation on secondary degeneration of somatic sensation conduction fibers in patients with chronic thalamic infarction |
| 投稿时间：2017-09-27 修订日期：2018-03-01 |
| DOI：10.13929/j.1003-3289.201709155 |
| 中文关键词: 丘脑 脑梗死 磁共振成像 |
| 英文关键词:Thalamus Brain infarction Magnetic resonance imaging |
| 基金项目:四川省教育厅重点项目（18ZA0211）、川北医学院博士启动基金（CBY16-QD04）。 |
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| 中文摘要: |
| 目的 观察慢性丘脑梗死患者躯体感觉传导纤维束继发性损害的DTI表现。方法 对28例单侧慢性丘脑梗死患者（TI组）及28名健康志愿者（对照组）行常规MR及DTI扫描，计算受检者脊髓丘脑束和丘脑中央辐射部分各向异性（FA）值、平均扩散量（MD）值和扩散本征（λ1、λ23）值，并进行统计学分析。结果 与对照组相比，TI组梗死灶下方脊髓丘脑束和上方丘脑中央辐射FA值降低（P均<0.001）；而MD值、λ1值及λ23值均升高（P均<0.05）。结论 丘脑梗死可致病灶下方脊髓丘脑束及上方丘脑中央辐射的继发性损害；且在梗死慢性期，脊髓丘脑束和丘脑中央辐射继发性损害的DTI表现相同。 |
| 英文摘要: |
| Objective To observe DTI manifestations of secondary damage of the somatic sensation conduction fiber bundles in patients with chronic thalamic infarction (TI). Methods Routine MRI and DTI were obtained in 28 patients with unilateral chronic TI (TI group) and 28 healthy volunteers (control group). The fractional anisotropy (FA) value, mean diffusivity (MD) value, primary eigenvalue (λ1) and transverse eigenvalue (λ23) of both spinothalamic tract and central thalamic radiation were calculated, and statistical analysis was performed. Results Compared with those in control group, the FA value of spinothalamic tract and central thalamic radiations significantly decreased (all P<0.001), while MD, λ1 and λ23 value significantly increased in TI group (all P<0.05). Conclusion TI can not only result in damage in spinothalamic tract below the infarct, but also cause deterioration in central thalamic radiations above the infarct. Moreover, the secondary damage of spinothalamic tract and central thalamic radiations present the same DTI manifestations in the chronic period. |
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